Anoctamin-8 (ANO8) Antibody
364€ (100 µg)
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935106861
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name
Anoctamin-8 (ANO8) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx230444
tested applications
ELISA, WB, IF/ICC
Description
ANO8 Antibody is a Rabbit Polyclonal against ANO8.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Anoctamin-8 (ANO8) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/200 - 1/2000, IF/ICC: 1/10 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IF/ICC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9HCE9 |
| Gene ID | 57719 |
| OMIM | 610216 |
| Alias | ANO8,KIAA1623,TMEM16H |
| Background | Antibody anti-ANO8 |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
ANO8, or TMEM16H, is a calcium-activated protein implicated in ion transport and membrane-related processes such as phospholipid scrambling and signal transduction. While its precise biological functions are not fully elucidated, ANO8 is expressed in various tissues, including the liver and immune system, where it is believed to regulate cellular signaling and calcium homeostasis. ANO8 may play roles in immune cell activation and lipid metabolism, contributing to cellular responses under stress or during inflammation. Dysregulation or mutations in ANO8 have been tentatively linked to metabolic disorders and immune dysfunctions, although further studies are needed to confirm its molecular mechanisms and physiological relevance.
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