ANO8 antibody

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935106861
info@markelab.com
name
ANO8 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00444
tested applications
ELISA, WB, IF
Description
Does not exhibit calcium-activated chloride channel(CaCC) activity.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | anoctamin 8 (ANO8) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | WB: 1:200-1:2000; IF: 1:10-1:100 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 136 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB, IF |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | Q9HCE9 |
Gene ID | 57719 |
Alias | ANO8,KIAA1623,TMEM16H |
Background | Antibody anti-ANO8 |
Status | RUO |
Note | Mol. Weight 136 kDa |
Descripción
ANO8, or TMEM16H, is a calcium-activated protein implicated in ion transport and membrane-related processes such as phospholipid scrambling and signal transduction. While its precise biological functions are not fully elucidated, ANO8 is expressed in various tissues, including the liver and immune system, where it is believed to regulate cellular signaling and calcium homeostasis. ANO8 may play roles in immune cell activation and lipid metabolism, contributing to cellular responses under stress or during inflammation. Dysregulation or mutations in ANO8 have been tentatively linked to metabolic disorders and immune dysfunctions, although further studies are needed to confirm its molecular mechanisms and physiological relevance.
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