Anoctamin 3 (ANO3) Antibody

Este producto es parte de ANO - Anoctamin
Product Graph
637€ (100 µl)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Anoctamin 3 (ANO3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx111005
tested applications
ELISA, WB

Description

Anoctamin 3 Antibody is a Rabbit Polyclonal antibody against Anoctamin 3.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Anoctamin 3 (ANO3)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Antigen Affinity Chromatography.
Size 1
100 µl
Form
Liquid
Tested Applications
ELISA, WB
Buffer
PBS, pH 7.3, containing 0.02% Sodium Azide and 50% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q9BYT9
Gene ID
63982
NCBI Accession
NP_001300655.1, NM_001313726.1, NP_001300656.1, NM_001313727.1
OMIM
610110
Alias
ANO3,C11orf25,TMEM16C
Background
Antibody anti-ANO3
Status
RUO

Descripción

ANO3, also known as TMEM16C, is a member of the anoctamin family with roles in neuronal signaling and ion channel regulation. ANO3 is expressed in specific regions of the nervous system, including motor neurons and sensory neurons, where it may regulate calcium signaling and ion fluxes critical for neuronal function. Mutations in ANO3 have been linked to dystonia, a neurological movement disorder characterized by involuntary muscle contractions, abnormal postures, and impaired motor control. ANO3’s role in modulating neuronal excitability and neurotransmitter release highlights its importance in maintaining normal motor neuron function. Dysregulation or mutations disrupt calcium signaling and neuronal communication, leading to motor dysfunction and neurodegenerative diseases.

Related Products

FNab00443

anti- ANO3 antibody

Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylcholine and galactosylceramide. Seems to act as potassium channel regulator and may inhibit pain signaling; can facilitate KCNT1/Slack channel activity by promoting its full single-channel conductance at very low sodium concentrations and by increasing its sodium sensitivity(By similarity). Does not exhibit calcium-activated chloride channel(CaCC) activity.

Ver Producto
abx111005

Anoctamin 3 (ANO3) Antibody

Anoctamin 3 Antibody is a Rabbit Polyclonal antibody against Anoctamin 3.

Ver Producto
abx230443

Anoctamin 3 (ANO3) Antibody

ANO3 Antibody is a Rabbit Polyclonal against ANO3.

Ver Producto