Anoctamin 3 (ANO3) Antibody

637€ (100 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Anoctamin 3 (ANO3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx111005
tested applications
ELISA, WB
Description
Anoctamin 3 Antibody is a Rabbit Polyclonal antibody against Anoctamin 3.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Anoctamin 3 (ANO3) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Antigen Affinity Chromatography. |
Size 1 | 100 µl |
Form | Liquid |
Tested Applications | ELISA, WB |
Buffer | PBS, pH 7.3, containing 0.02% Sodium Azide and 50% Glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q9BYT9 |
Gene ID | 63982 |
NCBI Accession | NP_001300655.1, NM_001313726.1, NP_001300656.1, NM_001313727.1 |
OMIM | 610110 |
Alias | ANO3,C11orf25,TMEM16C |
Background | Antibody anti-ANO3 |
Status | RUO |
Descripción
ANO3, also known as TMEM16C, is a member of the anoctamin family with roles in neuronal signaling and ion channel regulation. ANO3 is expressed in specific regions of the nervous system, including motor neurons and sensory neurons, where it may regulate calcium signaling and ion fluxes critical for neuronal function. Mutations in ANO3 have been linked to dystonia, a neurological movement disorder characterized by involuntary muscle contractions, abnormal postures, and impaired motor control. ANO3’s role in modulating neuronal excitability and neurotransmitter release highlights its importance in maintaining normal motor neuron function. Dysregulation or mutations disrupt calcium signaling and neuronal communication, leading to motor dysfunction and neurodegenerative diseases.
Related Products

anti- ANO3 antibody
Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylcholine and galactosylceramide. Seems to act as potassium channel regulator and may inhibit pain signaling; can facilitate KCNT1/Slack channel activity by promoting its full single-channel conductance at very low sodium concentrations and by increasing its sodium sensitivity(By similarity). Does not exhibit calcium-activated chloride channel(CaCC) activity.
Ver Producto
Anoctamin 3 (ANO3) Antibody
Anoctamin 3 Antibody is a Rabbit Polyclonal antibody against Anoctamin 3.
Ver Producto