Annexin A8-Like Protein 1 (ANXA8L2) Antibody
357.5€ (100 µg)
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935106861
info@markelab.com
name
Annexin A8-Like Protein 1 (ANXA8L2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx036302
tested applications
ELISA, WB, IHC
Description
Rabbit Polyclonal against the ANXA8L2 protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Annexin A8-Like Protein 1 (ANXA8L2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | ANXA8L1,ANXA8L2 |
| Background | Antibody anti-ANXA8L1 |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
ANXA8L1 is a member of the annexin family closely related to Annexin A8, sharing structural and functional similarities as a calcium-dependent phospholipid-binding protein. ANXA8L1 is involved in membrane dynamics, such as vesicle trafficking, endocytosis, and exocytosis, and regulates cell membrane integrity under stress conditions. It has been implicated in tumorigenesis, particularly in cancers such as breast cancer and leukemia, where its expression promotes cell survival, metastasis, and drug resistance. ANXA8L1 may also play roles in angiogenesis, influencing endothelial cell behavior and blood vessel formation. Dysregulation of ANXA8L1 contributes to abnormal signaling pathways, highlighting its importance in cancer progression and as a potential biomarker for therapeutic targeting.
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