Annexin A8-Like 2 (ANXA8L1) Antibody

637€ (100 µl)
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935106861
info@markelab.com
name
Annexin A8-Like 2 (ANXA8L1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx111001
tested applications
ELISA, WB
Description
Annexin A8-Like 2 Antibody is a Rabbit Polyclonal antibody against Annexin A8-Like 2.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Annexin A8-Like 2 (ANXA8L1) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Antigen Affinity Chromatography. |
Size 1 | 100 µl |
Form | Liquid |
Tested Applications | ELISA, WB |
Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q5VT79 |
Gene ID | 728113 |
NCBI Accession | NP_001092315.2, NM_001098845.2 |
Alias | ANXA8L1,ANXA8L2 |
Background | Antibody anti-ANXA8L1 |
Status | RUO |
Descripción
ANXA8L1 is a member of the annexin family closely related to Annexin A8, sharing structural and functional similarities as a calcium-dependent phospholipid-binding protein. ANXA8L1 is involved in membrane dynamics, such as vesicle trafficking, endocytosis, and exocytosis, and regulates cell membrane integrity under stress conditions. It has been implicated in tumorigenesis, particularly in cancers such as breast cancer and leukemia, where its expression promotes cell survival, metastasis, and drug resistance. ANXA8L1 may also play roles in angiogenesis, influencing endothelial cell behavior and blood vessel formation. Dysregulation of ANXA8L1 contributes to abnormal signaling pathways, highlighting its importance in cancer progression and as a potential biomarker for therapeutic targeting.
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