Ankyrin Repeat Domain 13C (ANKRD13C) Antibody

Background

ANKRD13C is a protein containing multiple ankyrin repeat domains that mediate protein-protein interactions and regulate the stability and localization of target proteins. ANKRD13C is implicated in the ubiquitin-proteasome system (UPS), where it helps recruit specific proteins for ubiquitination and subsequent proteasomal degradation. It plays a role in cellular protein quality control, ensuring the removal of damaged or misfolded proteins to maintain proteostasis. ANKRD13C has been linked to pathways regulating cell growth, survival, and stress responses. Dysregulation of ANKRD13C may contribute to pathological conditions, including cancer and neurodegeneration, where disrupted protein turnover leads to abnormal cellular accumulation or signaling imbalances. Its role in ubiquitin-dependent processes underscores its importance in maintaining cellular homeostasis.