Ankyrin Repeat Domain 13C (ANKRD13C) Antibody
292.5€ (80 µl)
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Name
Ankyrin Repeat Domain 13C (ANKRD13C) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx034245
Tested Applications
ELISA, WB, FCM
Description
ANKRD13C Antibody is a Rabbit Polyclonal antibody against ANKRD13C.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Ankyrin Repeat Domain 13C (ANKRD13C) Immunogen: KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human ANKRD13C. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 60.8 kDa |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, FCM |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8N6S4 |
| Alias | ANKRD13B |
| Background | Antibody anti-ANKRD13C |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ANKRD13C is a protein containing multiple ankyrin repeat domains that mediate protein-protein interactions and regulate the stability and localization of target proteins. ANKRD13C is implicated in the ubiquitin-proteasome system (UPS), where it helps recruit specific proteins for ubiquitination and subsequent proteasomal degradation. It plays a role in cellular protein quality control, ensuring the removal of damaged or misfolded proteins to maintain proteostasis. ANKRD13C has been linked to pathways regulating cell growth, survival, and stress responses. Dysregulation of ANKRD13C may contribute to pathological conditions, including cancer and neurodegeneration, where disrupted protein turnover leads to abnormal cellular accumulation or signaling imbalances. Its role in ubiquitin-dependent processes underscores its importance in maintaining cellular homeostasis.
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