ANKRD13C antibody
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935106861
info@markelab.com
name
ANKRD13C antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00408
tested applications
ELISA, WB, IHC
Description
Acts as a molecular chaperone for G protein-coupled receptors, regulating their biogenesis and exit from the ER.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ankyrin repeat domain 13C (ANKRD13C) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:200-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 61 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q8N6S4 |
| Gene ID | 81573 |
| Alias | ANKRD13B |
| Background | Antibody anti-ANKRD13C |
| Status | RUO |
| Note | Mol. Weight 61 kDa |
Descripción
ANKRD13C is a protein containing multiple ankyrin repeat domains that mediate protein-protein interactions and regulate the stability and localization of target proteins. ANKRD13C is implicated in the ubiquitin-proteasome system (UPS), where it helps recruit specific proteins for ubiquitination and subsequent proteasomal degradation. It plays a role in cellular protein quality control, ensuring the removal of damaged or misfolded proteins to maintain proteostasis. ANKRD13C has been linked to pathways regulating cell growth, survival, and stress responses. Dysregulation of ANKRD13C may contribute to pathological conditions, including cancer and neurodegeneration, where disrupted protein turnover leads to abnormal cellular accumulation or signaling imbalances. Its role in ubiquitin-dependent processes underscores its importance in maintaining cellular homeostasis.
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