Ankyrin Repeat Domain 13C (ANKRD13C) Antibody
364€ (100 µg)
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935106861
info@markelab.com
name
Ankyrin Repeat Domain 13C (ANKRD13C) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx230408
tested applications
ELISA, WB, IHC
Description
ANKRD13C Antibody is a Rabbit Polyclonal against ANKRD13C.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Ankyrin Repeat Domain 13C (ANKRD13C) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1/200 - 1/2000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8N6S4 |
| Gene ID | 81573 |
| OMIM | 615125 |
| Alias | ANKRD13B |
| Background | Antibody anti-ANKRD13C |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
ANKRD13C is a protein containing multiple ankyrin repeat domains that mediate protein-protein interactions and regulate the stability and localization of target proteins. ANKRD13C is implicated in the ubiquitin-proteasome system (UPS), where it helps recruit specific proteins for ubiquitination and subsequent proteasomal degradation. It plays a role in cellular protein quality control, ensuring the removal of damaged or misfolded proteins to maintain proteostasis. ANKRD13C has been linked to pathways regulating cell growth, survival, and stress responses. Dysregulation of ANKRD13C may contribute to pathological conditions, including cancer and neurodegeneration, where disrupted protein turnover leads to abnormal cellular accumulation or signaling imbalances. Its role in ubiquitin-dependent processes underscores its importance in maintaining cellular homeostasis.
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