Alpha-Ketoglutarate-Dependent Dioxygenase AlkB Homolog 6 (ALKBH6) Antibody

Este producto es parte de ALKBH - alkB homolog
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195€ (20 µl)

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935106861
info@markelab.com
name
Alpha-Ketoglutarate-Dependent Dioxygenase AlkB Homolog 6 (ALKBH6) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx135923
tested applications
ELISA, WB

Description

ALKBH6 Antibody is a Rabbit Polyclonal against ALKBH6.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Alpha-Ketoglutarate-Dependent Dioxygenase AlkB Homolog 6 (ALKBH6)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
ELISA: 1 µg/ml, WB: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by affinity chromatography.
Size 1
20 µl
Size 2
100 µl
Size 3
2 × 100 µl
Form
Liquid
Tested Applications
ELISA, WB
Buffer
PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q3KRA9
Gene ID
84964
NCBI Accession
NP_116267.3
Alias
ALKBH6,ABH6
Background
Antibody anti-ALKBH6
Status
RUO
Note
Concentration: > 0.2 mg/ml - 

Descripción

ALKBH6 is an α-KG- and Fe(II)-dependent dioxygenase whose precise biochemical and functional roles remain less defined compared to other ALKB family members. Preliminary evidence suggests that ALKBH6 may play a role in DNA and RNA repair, particularly in counteracting methylation damage caused by environmental alkylating agents. It is expressed in multiple tissues, including the liver, kidneys, and brain, where it is thought to contribute to cellular responses to genotoxic and oxidative stress. ALKBH6 may also participate in regulating cellular metabolism by linking α-KG availability to nucleic acid repair pathways. Its dysregulation has been associated with cellular stress and metabolic imbalances, suggesting a broader role in maintaining genomic integrity and energy homeostasis. Further studies are ongoing to elucidate its specific substrates and functional importance in health and disease.

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