Mouse Probable alpha-ketoglutarate-dependent dioxygenase ABH6 (ALKBH6) ELISA Kit

Este producto es parte de ALKBH - alkB homolog
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715€ (96 tests)

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935106861
info@markelab.com
name
Mouse Probable alpha-ketoglutarate-dependent dioxygenase ABH6 (ALKBH6) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx501566
tested applications
ELISA

Description

Mouse Probable alpha-ketoglutarate-dependent dioxygenase ABH6 (ALKBH6) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Probable alpha-ketoglutarate-dependent dioxygenase ABH6 concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Probable alpha-ketoglutarate-dependent dioxygenase ABH6 (ALKBH6)
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q8K2U2
Gene ID
233065
Alias
ALKBH6,ABH6
Background
Elisa kits for ALKBH6
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

ALKBH6 is an α-KG- and Fe(II)-dependent dioxygenase whose precise biochemical and functional roles remain less defined compared to other ALKB family members. Preliminary evidence suggests that ALKBH6 may play a role in DNA and RNA repair, particularly in counteracting methylation damage caused by environmental alkylating agents. It is expressed in multiple tissues, including the liver, kidneys, and brain, where it is thought to contribute to cellular responses to genotoxic and oxidative stress. ALKBH6 may also participate in regulating cellular metabolism by linking α-KG availability to nucleic acid repair pathways. Its dysregulation has been associated with cellular stress and metabolic imbalances, suggesting a broader role in maintaining genomic integrity and energy homeostasis. Further studies are ongoing to elucidate its specific substrates and functional importance in health and disease.

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