Human Probable alpha-ketoglutarate-dependent dioxygenase ABH6 (ALKBH6) ELISA Kit

Name: Human Probable alpha-ketoglutarate-dependent dioxygenase ABH6 (ALKBH6) ELISA Kit
Brand: Abbexa
SKU: abx501565
Price: 687.5 EUR
Availability: OnlineOnly

Este producto es parte de ALKBH - alkB homolog

Pida mas información

935106861

info@markelab.com

Precio

687.5€ (96 tests)

Elisa Kits ALKBH6

proveedor

Abbexa

reference

abx501565

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Probable alpha-ketoglutarate-dependent dioxygenase ABH6 (ALKBH6) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Probable alpha-ketoglutarate-dependent dioxygenase ABH6 (ALKBH6) concentrations in tissue homogenates, cell lysates and other biological fluids.

Background

ALKBH6 is an α-KG- and Fe(II)-dependent dioxygenase whose precise biochemical and functional roles remain less defined compared to other ALKB family members. Preliminary evidence suggests that ALKBH6 may play a role in DNA and RNA repair, particularly in counteracting methylation damage caused by environmental alkylating agents. It is expressed in multiple tissues, including the liver, kidneys, and brain, where it is thought to contribute to cellular responses to genotoxic and oxidative stress. ALKBH6 may also participate in regulating cellular metabolism by linking α-KG availability to nucleic acid repair pathways. Its dysregulation has been associated with cellular stress and metabolic imbalances, suggesting a broader role in maintaining genomic integrity and energy homeostasis. Further studies are ongoing to elucidate its specific substrates and functional importance in health and disease.

Características del producto

immunogen target

Probable alpha-ketoglutarate-dependent dioxygenase ABH6 (ALKBH6)

reactivity

Human

test range

0.156 ng/ml - 10 ng/ml

assay data

Quantitative

detection method

Colorimetric

sample type

Tissue homogenates,Cell lysates,Other biological fluids

size 1

96 tests

alias

ALKBH6,ABH6

storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit

or code

ALKBH6

dry ice

uniprot id

https://www.uniprot.org/uniprotkb/Q3KRA9

gene id

https://www.ncbi.nlm.nih.gov/gene/84964

note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

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Alpha-Ketoglutarate-Dependent Dioxygenase AlkB Homolog 6 (ALKBH6) Antibody

proveedor

Abbexa

reference

abx135923

Tested Applications

reactivity

Human, Mouse, Rat

status

RUO

clonality

Polyclonal

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