Aldehyde Dehydrogenase 8 Family Member A1 (ALDH8A1) Antibody
637€ (100 µl)
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935106861
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name
Aldehyde Dehydrogenase 8 Family Member A1 (ALDH8A1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx110923
tested applications
ELISA, WB
Description
Aldehyde Dehydrogenase 8 Family, Member A1 Antibody is a Rabbit Polyclonal antibody against Aldehyde Dehydrogenase 8 Family, Member A1.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Aldehyde Dehydrogenase 8 Family Member A1 (ALDH8A1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9H2A2 |
| Gene ID | 64577 |
| NCBI Accession | NP_001180409.1, NM_001193480.1, NP_072090.1, NM_022568.3 |
| OMIM | 606467 |
| Alias | ALDH8A1,ALDH12 |
| Background | Antibody anti-ALDH8A1 |
| Status | RUO |
Descripción
ALDH8A1 is a cytosolic enzyme primarily involved in the metabolism of retinaldehyde to retinoic acid, a key signaling molecule that regulates cell differentiation, growth, and tissue homeostasis. ALDH8A1 is expressed in metabolic tissues, including the liver, kidneys, and retina, where it supports retinoid metabolism and vitamin A homeostasis. Its role in converting retinaldehyde to retinoic acid makes ALDH8A1 critical for maintaining vision, embryonic development, and immune responses. Dysregulation of ALDH8A1 has been implicated in retinal diseases, such as age-related macular degeneration (AMD), and developmental abnormalities caused by retinoic acid deficiency. ALDH8A1 also participates in detoxifying aldehydes derived from lipid peroxidation and xenobiotic metabolism, contributing to cellular defense against oxidative stress. Emerging studies suggest its involvement in maintaining retinoid signaling pathways and redox balance.
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Aldehyde Dehydrogenase 8 Family Member A1 (ALDH8A1) Antibody
Rabbit Polyclonal against the ALDH8A1 protein.
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Aldehyde Dehydrogenase 8 Family, Member A1 Antibody is a Rabbit Polyclonal antibody against Aldehyde Dehydrogenase 8 Family, Member A1.
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