Aladin (AAAS) Antibody
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935106861
info@markelab.com
Precio
637€ (100 µl)
Antibody anti-AAAS
proveedor
Abbexareference
abx116774Tested Applications
ELISA, WB, IHC, IF/ICCreactivity
Human, Mouse, Ratstatus
RUOclonality
PolyclonalDescripción
Achalasia, Adrenocortical Insufficiency, Alacrimia (Allgrove, Triple-A) Antibody is a Rabbit Polyclonal antibody against Achalasia, Adrenocortical Insufficiency, Alacrimia (Allgrove, Triple-A).
Background
Aladin, also known as adracalin, is a nucleoporin that in humans is encoded by the AAAS gene, located on chromosome 12q13.Aladin is primarily expressed in the adrenal gland, brain, and peripheral nervous system. Mutations in the AAAS gene result in dysfunction or loss of function of the Aladin protein. It iwas linked to a triple A syndrome ( also known as Allgrove Syndrome) which occurs when the gene is mutated. The AAAs gene product is a protein of 60 Kd. Aladin is a component of the nuclear pore complex, to which it is attached by nucleoporin NDC1. Mutant aladin causes selective failure of nuclear protein import and hypersensitivity to oxidative stress
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human, Mouse, Rat
immunogen target
Aladin (AAAS)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB, IHC, IF/ICC
purification
Antigen Affinity Chromatography.
recommended dilution
Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol.
size 1
100 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
AAAS
dry ice
No
availability
Shipped within 5-10 working days.
alias
AAA,AAASb,GL003,ALADIN,ADRACALA,ADRACALIN
uniprot id
NCBI accession
NP_001166937.1, NM_001173466.1, NP_056480.1, NM_015665.5
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