AKT Interacting Protein (AKTIP) Antibody
377€ (100 µg)
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Name
AKT Interacting Protein (AKTIP) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx230274
Tested Applications
ELISA, WB, IHC
Description
AKTIP Antibody is a Rabbit Polyclonal against AKTIP.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: AKT Interacting Protein (AKTIP) Immunogen: AKT interacting protein |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: 2 mg/ml |
| Recommended Dilution | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 36 kDa |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9H8T0 |
| Alias | AKTIP,FTS |
| Background | Antibody anti-AKTIP |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
AKT Interacting Protein (AKTIP) is a multifunctional protein that plays a role in the regulation of cellular proliferation, survival, and DNA repair by interacting with AKT, a serine/threonine kinase involved in key signaling pathways. AKTIP is implicated in the maintenance of telomere integrity and genomic stability by facilitating telomere replication and protecting telomeres from damage. It also functions in vesicular trafficking and lipid metabolism, linking it to processes such as endosome dynamics and cellular energy homeostasis. Dysregulation of AKTIP is associated with genomic instability, which can lead to cancer progression and age-related diseases. AKTIP is also being studied for its role in insulin signaling and metabolic disorders due to its interaction with the AKT pathway. Research into AKTIP continues to uncover its broader implications in cellular signaling and its potential as a therapeutic target in cancer and metabolic dysfunction.
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