AGR2+AGR3 Antibody
455€ (0.1 mg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
AGR2+AGR3 Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx139990
tested applications
WB, IHC, IF/ICC
Description
AGR2+AGR3 Antibody is a Mouse Monoclonal against AGR2+AGR3.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | AGR2+AGR3 |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | Validated in IHC-P and ICC. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Clone ID | Q265 |
| Purity | > 95% (SDS-PAGE) |
| Purification | Purified by Protein A affinity chromatography. |
| Size 1 | 0.1 mg |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | Stabilizing PBS solution containing 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8°C. Do not freeze. |
| Dry Ice | No |
| UniProt ID | O95994 |
| Gene ID | 10551 |
| Alias | AG-2,AG2,GOB-4,HAG-2,HEL-S-116,HPC8 |
| Background | Antibody anti-AGR2 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
AGR2 is a protein involved in the endoplasmic reticulum (ER) stress response and functions as a protein disulfide isomerase (PDI), facilitating the proper folding of secreted and membrane proteins. It is primarily expressed in secretory tissues such as the gastrointestinal tract, lungs, and prostate, where it maintains ER homeostasis by catalyzing the formation of disulfide bonds in proteins. AGR2 also plays a role in cell adhesion and migration, partly through its interaction with mucins like MUC1 and MUC2. Overexpression of AGR2 is frequently observed in cancers, including breast, pancreatic, and prostate cancers, where it contributes to tumor progression, chemoresistance, and metastasis by promoting cell survival under stress conditions
Related Products
Human AGR2(Anterior Gradient Protein 2) ELISA Kit
Ver Producto
Mouse Agr2(Anterior gradient protein 2 homolog) ELISA Kit
Ver Producto
anti- AGR2 antibody
Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells(By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth.
Ver Producto