Adenylate Cyclase 1, Brain (ADCY1) Antibody (FITC)
Pida mas información
935106861
info@markelab.com
Precio
429€ (200 µl)
Antibody anti-ADCY1
proveedor
Abbexareference
abx274322Tested Applications
WB, IHC, IF/ICCreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
Adenylate Cyclase 1, Brain (ADCY1) Antibody (FITC) is a Rabbit Polyclonal antibody conjugated to FITC against Adenylate Cyclase 1, Brain (ADCY1).
Background
ADCY1 is a membrane-bound enzyme predominantly expressed in the brain, specifically in neuronal tissues. It is activated by G-protein-coupled receptors (GPCRs) and regulated by calcium/calmodulin, playing a vital role in generating cyclic AMP (cAMP), a second messenger critical for signal transduction. ADCY1 is essential for synaptic plasticity, learning, and memory processes. Dysregulation of ADCY1 has been linked to neurological disorders, such as cognitive impairments and epilepsy, due to impaired cAMP signaling pathways. Its expression and activity are crucial for calcium-dependent cAMP production in neurons.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Adenylate Cyclase 1, Brain (ADCY1)
host
Rabbit
isotype
IgG
conjugation
FITC
form
Liquid
tested applications
WB, IHC, IF/ICC
purification
Purified by antigen-specific affinity chromatography.
recommended dilution
WB: 0.5-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
buffer
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
size 1
200 µl
size 2
1 ml
storage
Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
or code
ADCY1
dry ice
No
availability
Shipped within 5-7 working days.
alias
AC1,DFNB44,ATP pyrophosphate-lyase 1
uniprot id
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