Acidic Nuclear Phosphoprotein 32 Family Member C (ANP32C) Antibody
221€ (50 µg)
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Name
Acidic Nuclear Phosphoprotein 32 Family Member C (ANP32C) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx323452
Tested Applications
ELISA, WB
Description
ANP32C Antibody is a Rabbit Polyclonal against ANP32C.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Acidic Nuclear Phosphoprotein 32 Family Member C (ANP32C) Immunogen: Synthesized peptide derived from the Internal region of human PP32R1. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/10000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O43423 |
| Gene ID | 23520 |
| Alias | ANP32C,PP32R1 |
| Background | Antibody anti-ANP32CP |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ANP32CP, also known as ANP32E, is a member of the ANP32 family that plays a significant role in histone dynamics and chromatin remodeling. ANP32CP regulates the exchange and deposition of histone H2A.Z, a histone variant that influences transcriptional regulation, DNA repair, and chromatin structure. By modulating H2A.Z localization, ANP32CP is involved in regulating gene expression, DNA damage response, and genomic stability. Its activity is crucial for cellular differentiation, proliferation, and stress adaptation. Dysregulation of ANP32CP has been associated with cancer, where altered histone dynamics promote transcriptional changes driving tumor progression. Its role in histone regulation highlights its significance in maintaining chromatin integrity and cellular homeostasis.
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