AarF Domain Containing Kinase 1 (ADCK1) Antibody

260€ (50 µl)
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935106861
info@markelab.com
name
AarF Domain Containing Kinase 1 (ADCK1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx212588
tested applications
ELISA, IHC
Description
ADCK1 Antibody is a Rabbit Polyclonal against ADCK1.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | AarF Domain Containing Kinase 1 (ADCK1) |
Host | Rabbit |
Reactivity | Human, Mouse |
Recommended Dilution | ELISA: 1/2000 - 1/5000, IHC: 1/25 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Antigen Affinity Chromatography. |
Size 1 | 50 µl |
Size 2 | 100 µl |
Form | Liquid |
Tested Applications | ELISA, IHC |
Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q86TW2 |
Gene ID | 57143 |
Alias | MCP2 |
Background | Antibody anti-ADCK1 |
Status | RUO |
Descripción
aarF domain-containing kinase 1 (ADCK1) is part of the atypical kinase family characterized by the presence of an aarF domain, which is involved in coenzyme Q (CoQ) biosynthesis. ADCK1 is thought to function in mitochondrial processes, particularly in regulating the synthesis and stabilization of CoQ, an essential molecule in the electron transport chain for ATP production. While the specific physiological roles of ADCK1 remain under investigation, its expression in tissues with high energy demands suggests a key role in mitochondrial energy metabolism. Dysregulation of ADCK1 has been implicated in disorders related to mitochondrial dysfunction, oxidative stress, and metabolic imbalances. Emerging studies also suggest ADCK1 may participate in cellular signaling pathways linking energy metabolism and stress responses.
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