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Complement component 5 (C5) is a critical protein in the complement system, part of the innate immune system that enhances the ability of antibodies and phagocytic cells to clear microbes and damaged cells from the organism, promote inflammation, and attack the pathogen's cell membrane. The C5 protein is synthesized as a single polypeptide that is cleaved into two chains, C5a and C5b, upon activation. The C5 gene is located on chromosome 9 and encodes a precursor protein of approximately 190 kDa.
The complement system is divided into three pathways: the classical, lectin, and alternative pathways. All three pathways converge at the activation of C3, which subsequently leads to the activation of C5. This activation is a pivotal event in the complement cascade, resulting in the generation of C5a, an anaphylatoxin, and C5b, which initiates the formation of the membrane attack complex (MAC).
Complement component 5 (C5) plays a crucial role in the immune system by participating in the formation of the membrane attack complex and mediating inflammatory responses through the generation of C5a. The protein's activity is essential for host defense mechanisms against infections, but dysregulation can lead to pathological conditions. Understanding the structure, function, and clinical implications of C5 has led to significant advancements in treating complement-mediated diseases.
complement C5
C5D,C5a,C5b,ECLZB,CPAMD4,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Proteins and Peptides, Primary Antibodies, ELISA Kits, CLIA Kits) relacionados con Complement C5
Se muestran ordenados por categorías para poder comparar cómodamente sus características principales. Esta tabla, que contiene un enlace con la ficha de cada producto, es exportable a Excel.
Esta página contiene 32 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
FineTest | C5 | EH0680 | Human C5(Complement C5) ELISA Kit | human | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich ELISA, Double Antibody | 3.125-200ng/ml | 96T | P01031 | RUO | ||
Abbexa | C5 | abx150869 | Human Complement C5 (C5) ELISA Kit | Human | Serum,Plasma,Other biological fluids | Sandwich | 3.12 ng/ml - 200 ng/ml | < 1.3 ng/ml | 662.5 | 96 tests | P01031 | RUO |
Abbexa | C5 | abx253641 | Human Complement C5 (C5) ELISA Kit | Human | Serum,Plasma,Other biological fluids | Sandwich | 78.1 pg/ml - 5000 pg/ml | 47 pg/ml | 556.25 | 96 tests | P01031 | RUO |
Abbexa | C5 | abx493313 | Human Complement C5 (C5) CLIA Kit | Human | Serum, plasma and other biological fluids. | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.136 ng/ml | 812.5 | 96 tests | P01031 | RUO |
Abbexa | C5 | abx359469 | Monkey Complement C5 (C5) ELISA Kit | Monkey | Serum,Plasma,Other biological fluids | Sandwich | 0.625 ng/ml - 40 ng/ml | 0.38 ng/ml | 662.5 | 96 tests | RUO | |
FineTest | C5 | EM0703 | Mouse C5(Complement C5) ELISA Kit | mouse | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich ELISA, Double Antibody | 0.156-10ng/ml | 96T | P06684 | RUO | ||
Abbexa | C5 | abx496327 | Mouse Complement C5 (C5) CLIA Kit | Mouse | Serum, plasma and other biological fluids. | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.149 ng/ml | 812.5 | 96 tests | P06684 | RUO |
Abbexa | C5 | abx255051 | Mouse Complement C5 (C5) ELISA Kit | Mouse | Serum,Plasma,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | 0.1 ng/ml | 562.5 | 96 tests | P06684 | RUO |
Abbexa | C5 | abx258736 | Mouse Complement C5 (C5) ELISA Kit | Mouse | Serum,Plasma,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.12 ng/ml | 618.75 | 96 tests | P06684 | RUO |
Abbexa | C5 | abx493314 | Mouse Complement C5 (C5) CLIA Kit | Mouse | Serum, plasma and other biological fluids. | Sandwich | 27.4 pg/ml - 20000 pg/ml | < 10.4 pg/ml | 812.5 | 96 tests | P06684 | RUO |
Abbexa | C5 | abx153740 | Mouse Complement C5 (C5) ELISA Kit | Mouse | Serum,Plasma,Other biological fluids | Sandwich | 12.5 ng/ml - 800 ng/ml | < 4.4 ng/ml | 675 | 96 tests | P06684 | RUO |
Abbexa | C5 | abx518979 | Low Sample Volume Mouse Complement C5 (C5) ELISA Kit | Mouse | Serum,Plasma,Other biological fluids | Sandwich | 12.5 ng/ml - 800 ng/ml | < 4.4 ng/ml | 787.5 | 96 tests | P06684 | RUO |
Abbexa | C5 | abx493315 | Rat Complement C5 (C5) CLIA Kit | Rat | Serum, plasma and other biological fluids. | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.148 ng/ml | 812.5 | 96 tests | P08650 | RUO |
Abbexa | C5 | abx256754 | Rat Complement C5 (C5) ELISA Kit | Rat | Serum,Plasma,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.1 ng/ml | 587.5 | 96 tests | P08650 | RUO |
Abbexa | C5 | abx155282 | Rat Complement C5 (C5) ELISA Kit | Rat | Serum,Plasma,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.15 ng/ml | 687.5 | 96 tests | P08650 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | C5 | abx034006 | Complement C5 (C5) Antibody | Human | Polyclonal | Rabbit | Complement C5 (C5) | Unconjugated | ELISA, WB, IHC, FCM | 281.25 | 80 µl | P01031 | RUO | |
Abbexa | C5 | abx301145 | Complement C5 (C5) Antibody | Human | Polyclonal | Rabbit | Complement C5 (C5) | Unconjugated | ELISA, IHC | 162.5 | 20 µg | P01031 | RUO | |
Abbexa | C5 | abx349858 | Complement C5 (C5) Antibody | Human | Monoclonal | Mouse | Complement C5 (C5) | Unconjugated | ELISA, FCM | 287.5 | 50 µl | P01031 | RUO | |
Abbexa | C5 | abx101999 | Complement C5 (C5) Antibody | Human | Polyclonal | Rabbit | Complement C5 (C5) | Unconjugated | WB, IHC, IF/ICC | 262.5 | 100 µl | P01031 | RUO | |
Abbexa | C5 | abx171888 | Complement C5 (C5) Antibody | Human | Monoclonal | Mouse | Complement C5 (C5) | Unconjugated | WB, IHC, IF/ICC | 750 | 1 ml | P01031 | RUO | |
Abbexa | C5 | abx005682 | Complement C5 (C5) Antibody | Human | Polyclonal | Rabbit | Complement C5 (C5) | Unconjugated | WB | 175 | 20 µl | P01031 | RUO | |
Abbexa | C5 | abx175980 | Complement C5 (C5) Antibody | Mouse | Polyclonal | Rabbit | Complement C5 (C5) | Unconjugated | WB, IHC, IF/ICC | 725 | 1 ml | P06684 | RUO | |
Abbexa | C5 | abx110613 | Complement C5 (C5) Antibody | Pig | Polyclonal | Rabbit | Complement C5 (C5) | Unconjugated | ELISA, IHC | 162.5 | 20 µg | P01032 | RUO | |
Abbexa | C5 | abx107760 | Complement C5 (C5) Antibody (FITC) | Pig | Polyclonal | Rabbit | Complement C5 (C5) | FITC | 162.5 | 20 µg | P01032 | RUO | ||
Abbexa | C5 | abx106347 | Complement C5 (C5) Antibody (Biotin) | Pig | Polyclonal | Rabbit | Complement C5 (C5) | Biotin | ELISA | 162.5 | 20 µg | P01032 | RUO | |
Abbexa | C5 | abx109177 | Complement C5 (C5) Antibody (HRP) | Pig | Polyclonal | Rabbit | Complement C5 (C5) | HRP | ELISA | 162.5 | 20 µg | P01032 | RUO | |
Abbexa | C5 | abx171889 | Complement C5 (C5) Antibody | Rat | Monoclonal | Mouse | Complement C5 (C5) | Unconjugated | WB, IHC, IF/ICC | 812.5 | 1 ml | P08650 | RUO | |
Abbexa | C5 | abx175982 | Complement C5 (C5) Antibody | Rat | Polyclonal | Rabbit | Complement C5 (C5) | Unconjugated | WB, IHC, IF/ICC | 775 | 1 ml | P08650 | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
FineTest | C5 | P4385 | Recombinant Human C5 | Human | Recombinant | E.Coli | Western Blot,ELISA | 50μg | P01031 | RUO | ||
Abbexa | C5 | abx652184 | Rat Complement C5 (C5) Protein | Rat | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 325 | 10 µg | P08650 | RUO |
FineTest | C5 | P4534 | Recombinant Mouse C5 | Mouse | Recombinant | E.Coli | Western Blot,ELISA | 50μg | P06684 | RUO | ||
Abbexa | C5 | abx652183 | Mouse Complement C5 (C5) Protein | Mouse | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 237.5 | 10 µg | P06684 | RUO |
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