Mouse Complement C5a (C5a) Protein

234€ (2 µg)
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name
Mouse Complement C5a (C5a) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx262470
tested applications
SDS-PAGE
Description
C5a is a recombinant protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Proteins and Peptides |
Immunogen Target | Complement C5a (C5a) |
Host | E. coli |
Origin | Mouse |
Conjugation | Unconjugated |
Expression | Recombinant |
Purity | > 95% (SDS-PAGE and RP-HPLC) |
Size 1 | 2 µg |
Size 2 | 10 µg |
Size 3 | 1 mg |
Form | Lyophilized |
Tested Applications | SDS-PAGE |
Availability | Shipped within 5-10 working days. |
Dry Ice | No |
UniProt ID | P06684 |
Alias | C5D,C5a,C5b,ECLZB,CPAMD4,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4 |
Background | Protein C5 |
Status | RUO |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
C5 is a central component of the complement system and plays a key role in the final steps of the complement cascade C5 is cleaved into C5a and C5b, with C5a acting as a potent inflammatory mediator that recruits immune cells to sites of infection or injury, and C5b contributing to the formation of the membrane attack complex (MAC), which leads to the lysis of pathogens C5 is involved in both innate and adaptive immune responses, helping to clear pathogens, regulate inflammation, and promote tissue repair Dysfunction in C5 or its components is associated with several diseases, including complement deficiencies, where insufficient activation leads to increased susceptibility to infections, and autoimmune disorders like atypical hemolytic uremic syndrome (aHUS) Studies also suggest that C5 plays a role in cancer progression, where its activity can influence immune evasion and tumor microenvironment regulation
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