Mouse Complement C5a (C5a) Protein

Este producto es parte de Complement C5
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234€ (2 µg)

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935106861
info@markelab.com
name
Mouse Complement C5a (C5a) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx262470
tested applications
SDS-PAGE

Description

C5a is a recombinant protein.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Complement C5a (C5a)
Host
E. coli
Origin
Mouse
Conjugation
Unconjugated
Expression
Recombinant
Purity
> 95% (SDS-PAGE and RP-HPLC)
Size 1
2 µg
Size 2
10 µg
Size 3
1 mg
Form
Lyophilized 
Tested Applications
SDS-PAGE
Availability
Shipped within 5-10 working days.
Dry Ice
No
UniProt ID
P06684
Alias
C5D,C5a,C5b,ECLZB,CPAMD4,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4
Background
Protein C5
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

C5 is a central component of the complement system and plays a key role in the final steps of the complement cascade C5 is cleaved into C5a and C5b, with C5a acting as a potent inflammatory mediator that recruits immune cells to sites of infection or injury, and C5b contributing to the formation of the membrane attack complex (MAC), which leads to the lysis of pathogens C5 is involved in both innate and adaptive immune responses, helping to clear pathogens, regulate inflammation, and promote tissue repair Dysfunction in C5 or its components is associated with several diseases, including complement deficiencies, where insufficient activation leads to increased susceptibility to infections, and autoimmune disorders like atypical hemolytic uremic syndrome (aHUS) Studies also suggest that C5 plays a role in cancer progression, where its activity can influence immune evasion and tumor microenvironment regulation

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