Family main features
Bradykinin receptors are a class of G protein-coupled receptors (GPCRs) that respond to the peptide hormone bradykinin. These receptors play important roles in various physiological processes, including vasodilation, inflammation, pain perception, and tissue repair.
Bradykinin receptors, like other GPCRs, consist of seven transmembrane domains and possess an extracellular N-terminus and an intracellular C-terminus. Upon ligand binding, conformational changes in the receptor initiate intracellular signaling cascades through interaction with heterotrimeric G proteins. Bradykinin, a peptide hormone generated from the precursor kininogen, serves as the endogenous ligand for bradykinin receptors. It is produced locally at sites of tissue injury or inflammation and binds to and activates B1 and B2 receptors, eliciting physiological responses.
There are two primary subtypes of bradykinin receptors:
Bradykinin receptors mediate various physiological effects in different tissues and organ systems:
Dysregulation of bradykinin receptor signaling is associated with various pathological conditions:
Bradykinin receptors represent potential targets for therapeutic intervention in various diseases. Pharmacological modulation of bradykinin receptor activity, either through agonists, antagonists, or allosteric modulators, holds promise for the development of novel therapies targeting these receptors.
Bradykinin Receptor B1 (BDKRB1)
BDKRB1,B1BKR,BKR1,B1R,bradykinin receptor,BKB1R,BRADYB1
Bradykinin receptor B2 (BDKRB2)
BDKRB2,B2BKR,B2BRA,BK-2 receptor.BK2R,bradykinin receptor, B2
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Primary Antibodies, ELISA Kits, Proteins and Peptides, CLIA Kits) relacionados con BDKRB - Bradykinin Receptor B
Se muestran ordenados por categorías para poder comparar cómodamente sus características principales. Esta tabla, que contiene un enlace con la ficha de cada producto, es exportable a Excel.
Esta página contiene 18 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
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Abbexa | BDKRB1 | abx503808 | Human B1 Bradykinin Receptor (BDKRB1) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.78 ng/ml - 50 ng/ml | < 0.31 ng/ml | 687.5 | 96 tests | P46663 | RUO |
Abbexa | BDKRB2 | abx585599 | Human Bradykinin Receptor B2 (BDKRB2) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.06 ng/ml | 687.5 | 96 tests | RUO | |
Abbexa | BDKRB1 | abx503809 | Mouse B1 Bradykinin Receptor (BDKRB1) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q61125 | RUO | |
Abbexa | BDKRB2 | abx585600 | Mouse Bradykinin Receptor B2 (BDKRB2) ELISA Kit | Mouse | Tissue homogenates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.06 ng/ml | 687.5 | 96 tests | RUO | |
Abbexa | BDKRB1 | abx503812 | Rat B1 Bradykinin Receptor (BDKRB1) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | P97583 | RUO | |
Abbexa | BDKRB2 | abx493629 | Rat Bradykinin Receptor B2 (BDKRB2) CLIA Kit | Rat | Tissue homogenates, cell lysates and other biological fluids. | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.056 ng/ml | 812.5 | 96 tests | RUO | |
Abbexa | BDKRB2 | abx155250 | Rat Bradykinin Receptor B2 (BDKRB2) ELISA Kit | Rat | Tissue homogenates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.06 ng/ml | 687.5 | 96 tests | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
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Abbexa | BDKRB1 | abx432423 | Bradykinin Receptor B1 (BDKRB1) Antibody | Human | Polyclonal | Goat | Bradykinin Receptor B1 (BDKRB1) | Unconjugated | P-ELISA, WB | 387.5 | 200 µl | RUO | ||
Abbexa | BDKRB1 | abx034082 | B1 Bradykinin Receptor (BDKRB1) Antibody | Human | Polyclonal | Rabbit | B1 Bradykinin Receptor (BDKRB1) | Unconjugated | ELISA, WB, FCM | 281.25 | 80 µl | P46663 | RUO | |
Abbexa | BDKRB1 | abx324342 | Bradykinin Receptor B1 (BDKRB1) Antibody | Human | Polyclonal | Rabbit | Bradykinin Receptor B1 (BDKRB1) | Unconjugated | ELISA, WB, IF/ICC | 187.5 | 50 µg | P46663 | RUO | |
Abbexa | BDKRB2 | abx334789 | Bradykinin Receptor B2 (BDKRB2) Antibody (FITC) | Human | Polyclonal | Rabbit | Bradykinin Receptor B2 (BDKRB2) | FITC | 162.5 | 20 µg | P30411 | RUO | ||
Abbexa | BDKRB2 | abx334790 | Bradykinin Receptor B2 (BDKRB2) Antibody (Biotin) | Human | Polyclonal | Rabbit | Bradykinin Receptor B2 (BDKRB2) | Biotin | ELISA | 162.5 | 20 µg | P30411 | RUO | |
Abbexa | BDKRB2 | abx338401 | Bradykinin Receptor B2 (BDKRB2) Antibody | Human | Polyclonal | Rabbit | Bradykinin Receptor B2 (BDKRB2) | Unconjugated | ELISA, WB, IF/ICC | 162.5 | 20 µg | P30411 | RUO | |
Abbexa | BDKRB2 | abx334788 | Bradykinin Receptor B2 (BDKRB2) Antibody (HRP) | Human | Polyclonal | Rabbit | Bradykinin Receptor B2 (BDKRB2) | HRP | ELISA | 162.5 | 20 µg | P30411 | RUO | |
Abbexa | BDKRB2 | abx242198 | Bradykinin Receptor B2 (BDKRB2) Antibody | Human | Polyclonal | Rabbit | Bradykinin Receptor B2 (BDKRB2) | Unconjugated | ELISA, WB, IHC | 250 | 50 µl | P30411 | RUO | |
Abbexa | BDKRB2 | abx241775 | Bradykinin Receptor B2 (BDKRB2) Antibody | Human | Polyclonal | Rabbit | Bradykinin Receptor B2 (BDKRB2) | Unconjugated | ELISA, WB, IHC | 250 | 50 µl | P30411 | RUO | |
Abbexa | BDKRB2 | abx006762 | Bradykinin Receptor B2 (BDKRB2) Antibody | Human | Polyclonal | Rabbit | Bradykinin Receptor B2 (BDKRB2) | Unconjugated | WB, IF/ICC | 175 | 20 µl | P30411 | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | BDKRB2 | abx652701 | Rat Bradykinin Receptor B2 (BDKRB2) Protein | Rat | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 1800 | 1 mg | RUO |
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