Mouse Bradykinin Receptor B2 (BDKRB2) ELISA Kit

Este producto es parte de BDKRB - Bradykinin Receptor B
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715€ (96 tests)

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935106861
info@markelab.com
name
Mouse Bradykinin Receptor B2 (BDKRB2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx585600
tested applications
ELISA

Description

Mouse Bradykinin Receptor B2 (BDKRB2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Bradykinin Receptor B2 (BDKRB2) concentrations in tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Bradykinin Receptor B2 (BDKRB2)

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Bradykinin Receptor B2 (BDKRB2)
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.156 ng/ml - 10 ng/ml
Sensitivity
< 0.06 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates and other biological fluids.
Availability
Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
Alias
BDKRB2,B2BKR,B2BRA,BK-2 receptor.BK2R,bradykinin receptor, B2
Background
Elisa kits for BDKRB2
Status
RUO
Note
Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Bradykinin Receptor B2 (BDKRB2) is a constitutively expressed GPCR that binds bradykinin, a peptide involved in the regulation of inflammatory responses, vasodilation, and pain signaling. BDKRB2 is widely expressed in endothelial cells, smooth muscle cells, and neurons, where it mediates vasodilation by stimulating the production of nitric oxide (NO) and prostacyclins. These effects help maintain blood flow and regulate vascular tone. In addition to its cardiovascular roles, BDKRB2 is involved in pain perception and edema formation during acute inflammation by increasing vascular permeability. In the kidneys, BDKRB2 contributes to sodium excretion and the regulation of blood pressure through the renin-angiotensin-aldosterone system (RAAS). Dysregulation of BDKRB2 has been implicated in hypertension, pulmonary edema, and inflammatory diseases, such as asthma and rheumatoid arthritis. BDKRB2 also plays roles in cancer biology, where its activation can promote tumor angiogenesis and invasion. Pharmacological modulation of BDKRB2 signaling, either through agonists or antagonists, has potential therapeutic applications for cardiovascular diseases, pain management, and inflammatory conditions.

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