Family main features
BCL2L1, also known as BCL-XL (B-cell lymphoma-extra large), is a member of the BCL2 protein family that plays a crucial role in regulating apoptosis. BCL2L1 was identified due to its homology with the BCL2 gene and is located on chromosome 20q11.21. This gene produces two main isoforms through alternative splicing: BCL-XL, which is anti-apoptotic, and BCL-XS, which is pro-apoptotic. BCL-XL is widely expressed in various tissues, including the hematopoietic system, nervous system, and epithelial tissues, indicating its importance in cell survival and homeostasis.
The structure of BCL2L1 is characterized by the presence of four BCL2 homology (BH) domains:
BCL2L1 belongs to the BCL2 protein family, which includes:
BCL2L1 (BCL-XL) primarily functions to inhibit apoptosis, thus promoting cell survival under various stress conditions:
Dysregulation of BCL2L1 has significant implications in various diseases:
BCL2L1 (BCL-XL) is a vital regulator of apoptosis, essential for maintaining cellular homeostasis and promoting cell survival under stress. It inhibits pro-apoptotic proteins, preserves mitochondrial integrity, and plays a critical role in various physiological processes. Dysregulation of BCL2L1 is associated with multiple diseases, particularly cancers and neurodegenerative disorders, making it a potential therapeutic target for developing treatments for these conditions. Understanding the function and regulation of BCL2L1 is crucial for advancing therapeutic strategies in oncology and neurobiology.
BCL2 like 1 (BCL2L1)
BCLX,BCL2L,Bcl-X,PPP1R52; BCL-XL/S,Apoptosis regulator Bcl-X
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Proteins and Peptides, ELISA Kits, Primary Antibodies, CLIA Kits) relacionados con BCL2L1 - BCL2 like 1
Se muestran ordenados por categorías para poder comparar cómodamente sus características principales. Esta tabla, que contiene un enlace con la ficha de cada producto, es exportable a Excel.
Esta página contiene 29 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
Contacta con nosotros en info@markelab.com, si necesitas mas informacion o alguna aclaracion. Te garantizamos respuesta en menos de 24 h.
provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | BCL2L1 | abx356067 | Chicken Bcl-2-Like Protein 1 / BCL-X (BCL2L1) ELISA Kit | Chicken | Serum,Plasma,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | 0.19 ng/ml | 662.5 | 96 tests | RUO | |
Abbexa | BCL2L1 | abx252076 | Human Bcl2 Like Protein 1 (BCL2L1) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | 0.19 ng/ml | 556.25 | 96 tests | Q07817 | RUO |
Abbexa | BCL2L1 | abx196478 | Human Bcl2 Like Protein 1 (BCL2L1) CLIA Kit | Human | Serum, plasma and other biological fluids. | Sandwich | 62.5 pg/ml - 4000 pg/ml | 37.5 pg/ml | 618.75 | 96 tests | RUO | |
Abbexa | BCL2L1 | abx503317 | Human Bcl-2-Like Protein 1 / BCL-X (BCL2L1) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.113 ng/ml | 618.75 | 96 tests | RUO | |
Abbexa | BCL2L1 | abx153705 | Mouse Bcl2 Like Protein 1 (BCL2L1) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 7.81 pg/ml - 500 pg/ml | < 3.1 pg/ml | 618.75 | 96 tests | RUO | |
Abbexa | BCL2L1 | abx361136 | Pig Bcl-2-Like Protein 1 / BCL-X (BCL2L1) ELISA Kit | Pig | Serum,Plasma,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | 0.19 ng/ml | 687.5 | 96 tests | RUO | |
Abbexa | BCL2L1 | abx362956 | Rabbit Bcl-2-Like Protein 1 / BCL-X (BCL2L1) ELISA Kit | Rabbit | Serum,Plasma,Other biological fluids | Sandwich | 125 pg/ml - 8000 pg/ml | 75 pg/ml | 662.5 | 96 tests | RUO | |
Abbexa | BCL2L1 | abx363903 | Rat Bcl2 Like Protein 1 (BCL2L1) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | 0.19 ng/ml | 587.5 | 96 tests | P53563 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FineTest | BCL2L1 | FNab00843 | anti- BCL2L1 antibody | human | monoclonal | Mouse | BCL2-like 1 | IgG2a | Unconjugated | ELISA, WB, IHC, IF | 100µg | Q07817 | RUO | |
FineTest | BCL2L1 | FNab00842 | anti- BCL2L1 antibody | human | polyclonal | Rabbit | BCL2-like 1 | IgG | Unconjugated | ELISA, IHC, IP, IF, WB | 100µg | Q07817 | RUO | |
Abbexa | BCL2L1 | abx210144 | Bcl-2-Like Protein 1 (BCL2L1) Antibody | Human | Monoclonal | Mouse | Bcl-2-Like Protein 1 (BCL2L1) | Unconjugated | ELISA, WB, IHC | 281.25 | 50 µg | Q07817 | RUO | |
Abbexa | BCL2L1 | abx106597 | BCL2 Like 1 (BCL2L1) Antibody (FITC) | Human | Polyclonal | Rabbit | BCL2 Like 1 (BCL2L1) | FITC | 162.5 | 20 µg | Q07817 | RUO | ||
Abbexa | BCL2L1 | abx230843 | Bcl-2-Like Protein 1 (BCL2L1) Antibody | Human | Monoclonal | Mouse | Bcl-2-Like Protein 1 (BCL2L1) | Unconjugated | ELISA, WB, IHC, IF/ICC | 350 | 100 µg | Q07817 | RUO | |
Abbexa | BCL2L1 | abx108014 | BCL2 Like 1 (BCL2L1) Antibody (HRP) | Human | Polyclonal | Rabbit | BCL2 Like 1 (BCL2L1) | HRP | ELISA | 162.5 | 20 µg | Q07817 | RUO | |
Abbexa | BCL2L1 | abx105180 | BCL2 Like 1 (BCL2L1) Antibody (Biotin) | Human | Polyclonal | Rabbit | BCL2 Like 1 (BCL2L1) | Biotin | ELISA | 162.5 | 20 µg | Q07817 | RUO | |
Abbexa | BCL2L1 | abx109263 | Bcl-2-Like Protein 1 (BCL2L1) Antibody | Human | Polyclonal | Rabbit | Bcl-2-Like Protein 1 (BCL2L1) | Unconjugated | ELISA, WB, IHC, IF/ICC | 162.5 | 20 µg | Q07817 | RUO | |
Abbexa | BCL2L1 | abx230842 | Bcl-2-Like Protein 1 (BCL2L1) Antibody | Human | Polyclonal | Rabbit | Bcl-2-Like Protein 1 (BCL2L1) | Unconjugated | ELISA, WB, IHC, IF/ICC, IP | 350 | 100 µg | Q07817 | RUO | |
Abbexa | BCL2L1 | abx326608 | BCL2 Like 1 (BCL2L1) Antibody | Human | Polyclonal | Rabbit | BCL2 Like 1 (BCL2L1) | Unconjugated | ELISA, IHC | 187.5 | 50 µg | Q07817 | RUO | |
Abbexa | BCL2L1 | abx116988 | Bcl-2-Like Protein 1 (BCL2L1) Antibody | Human | Polyclonal | Rabbit | Bcl-2-Like Protein 1 (BCL2L1) | Unconjugated | ELISA, WB, IHC | 450 | 100 µl | Q07817 | RUO | |
Abbexa | BCL2L1 | abx034903 | Bcl-2-Like Protein 1 (BCL2L1) Antibody | Human | Monoclonal | Mouse | Bcl-2-Like Protein 1 (BCL2L1) | Unconjugated | ELISA, WB | 281.25 | 80 µl | Q07817 | RUO | |
Abbexa | BCL2L1 | abx111195 | BCL2 Like 1 (BCL2L1) Antibody | Human | Polyclonal | Rabbit | BCL2 Like 1 (BCL2L1) | Unconjugated | ELISA, WB, IHC | 612.5 | 100 µl | Q07817 | RUO | |
Abbexa | BCL2L1 | abx328194 | BCL2 Like 1 (BCL2L1) Antibody | Human | Polyclonal | Rabbit | BCL2 Like 1 (BCL2L1) | Unconjugated | ELISA, WB, IHC | 187.5 | 50 µg | Q07817 | RUO | |
Abbexa | BCL2L1 | abx326842 | BCL2 Like 1 (BCL2L1) Antibody | Human | Polyclonal | Rabbit | BCL2 Like 1 (BCL2L1) | Unconjugated | IHC | 187.5 | 50 µg | Q07817 | RUO | |
Abbexa | BCL2L1 | abx329566 | BCL2 Like 1 (BCL2L1) Antibody | Human | Polyclonal | Rabbit | BCL2 Like 1 (BCL2L1) | Unconjugated | ELISA, WB, IHC, IF/ICC | 187.5 | 50 µg | Q07817 | RUO | |
Abbexa | BCL2L1 | abx402166 | Bcl-2-like protein 1 (BCL2L1) Antibody | Human | Monoclonal | Rabbit | Bcl-2-like protein 1 (BCL2L1) | Unconjugated | ELISA, WB, IHC | 287.5 | 50 µl | Q07817 | RUO | |
Abbexa | BCL2L1 | abx214806 | BCL2 Like 1 (BCL2L1) Antibody | Human | Polyclonal | Rabbit | BCL2 Like 1 (BCL2L1) | Unconjugated | ELISA, WB | 250 | 50 µl | Q07817 | RUO | |
Abbexa | BCL2L1 | abx242257 | BCL2 Like 1 (BCL2L1) Antibody | Human | Polyclonal | Rabbit | BCL2 Like 1 (BCL2L1) | Unconjugated | ELISA, WB | 250 | 50 µl | Q07817 | RUO | |
Abbexa | BCL2L1 | abx000597 | Bcl-2-Like Protein 1 (BCL2L1) Antibody | Human | Polyclonal | Rabbit | Bcl-2-Like Protein 1 (BCL2L1) | Unconjugated | WB, IHC, IF/ICC | 175 | 20 µl | Q07817 | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | BCL2L1 | abx680359 | Mouse Bcl2 Like Protein 1 (BCL2L1) Protein | Mouse | Recombinant | E. coli | Unconjugated | SDS-PAGE | 225 | 5 µg | RUO |
Te recomendamos que si no encuentras lo que buscas, utilices el buscador, refinando la búsqueda según tu criterio y usando Alias, o bien contacta con nosotros.