Bcl-2-Like Protein 1 (BCL2L1) Antibody

Este producto es parte de BCL2L1 - BCL2 like 1
Bcl-2-Like Protein 1 (BCL2L1) Antibody

Pida mas información

935106861

info@markelab.com

Precio

281.25€ (50 µg)

Antibody anti-BCL2L1

proveedor

Abbexa

reference

abx210144

Tested Applications

ELISA, WB, IHC

reactivity

Human

status

RUO

clonality

Monoclonal

Descripción

Bcl-2-like protein 1 Antibody is a Mouse Monoclonal against Bcl-2-like protein 1.


Background

BCL2 like 1 (BCL2L1), also known as BCL-XL, is a well-known anti-apoptotic protein that regulates cell survival by preventing mitochondrial apoptosis BCL2L1 is part of the Bcl-2 family of proteins, which includes both pro- and anti-apoptotic members, and it plays a crucial role in inhibiting the release of cytochrome c from mitochondria, thus blocking caspase activation and preventing apoptosis BCL2L1 is highly expressed in various cell types, including immune cells, neurons, and cancer cells, where it supports cell survival and promotes tissue homeostasis Dysregulation of BCL2L1 has been associated with cancer, where its overexpression protects tumor cells from chemotherapy-induced apoptosis and promotes tumor progression In addition to its role in cancer, BCL2L1 is involved in regulating immune responses and neuronal function, particularly in protecting against neurodegenerative diseases like Alzheimer’s and Parkinson’s Recent studies also highlight its importance in cell metabolism, autophagy, and inflammation, further emphasizing its role as a critical regulator of cellular fate and survival

Características del producto

category

Primary Antibodies


clonality

Monoclonal


reactivity

Human


immunogen target

Bcl-2-Like Protein 1 (BCL2L1)


host

Mouse


conjugation

Unconjugated


form

Liquid


tested applications

ELISA, WB, IHC


purity

> 95%


purification

Purified by Protein G.


buffer

0.01 M PBS, pH 7.4, 0.03% Proclin 300 and 50% glycerol.


size 1

50 µg


size 2

100 µg


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

BCL2L1


dry ice

No


availability

Shipped within 5-10 working days.


alias

BCLX,BCL2L,Bcl-X,PPP1R52; BCL-XL/S,Apoptosis regulator Bcl-X 


NCBI accession

NP_001182.1, NM_001191.3, NP_001304848.1, NM_001317919.1


note

This product is for research use only.


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