Family main features
AAK1, also known as AP2 Associated Protein Kinase 1, is a serine/threonine protein kinase encoded by the AAK1 gene. It is part of the NAK (Numb-Associated Kinase) family of protein kinases and is involved in various cellular processes, including endocytosis, vesicle trafficking, and signaling pathways.AAK1, is involved in endocytosis, vesicle trafficking, and signaling pathways. It regulates clathrin-mediated endocytosis by phosphorylating key components of the endocytic machinery and participates in intracellular vesicle trafficking and signaling cascades. Dysregulation of AAK1 has been implicated in cancer, neurological disorders, and infectious diseases, highlighting its significance as a potential therapeutic target in various pathological conditions. Further research into the molecular mechanisms underlying AAK1 function and its implications for disease may provide insights into novel therapeutic strategies for treating these conditions.
AAK1 is a multidomain protein kinase that contains several functional domains, including a protein kinase domain, a clathrin-binding domain, and multiple protein-protein interaction motifs. These domains enable AAK1 to interact with various binding partners and substrates involved in endocytosis and vesicle trafficking.
AAK1 belongs to the NAK (Numb-Associated Kinase) family of protein kinases, which also includes cyclin G-associated kinase (GAK) and NAK-related kinase (NRK). While there are no known subtypes of AAK1, it shares structural and functional similarities with other NAK family members.
AP2 Associated Protein Kinase 1(AAK1 )
AAK1,AP2 associated kinase 1
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Esta página contiene 14 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
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FineTest | AAK1 | EH13909 | Human AAK1(AP2-associated protein kinase 1) ELISA Kit | human | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich ELISA, Double Antibody | 0.156-10ng/ml | 96T | Q2M2I8 | RUO | ||
Abbexa | AAK1 | abx384534 | Human AP2 Associated Protein Kinase 1 (AAK1) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.1 ng/ml | 687.5 | 96 tests | Q2M2I8 | RUO |
Abbexa | AAK1 | abx595875 | AP2 Associated Protein Kinase 1 (AAK1) Cell ELISA Kit | Human | Cell ELISA | 493.75 | 96 tests | Q2M2I8 | RUO | |||
Abbexa | AAK1 | abx388480 | Mouse AP2 Associated Protein Kinase 1 (AAK1) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.094 ng/ml | 687.5 | 96 tests | Q3UHJ0 | RUO |
Abbexa | AAK1 | abx390913 | Rat AP2 Associated Protein Kinase 1 (AAK1) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 78 pg/ml - 5000 pg/ml | < 46.9 pg/ml | 687.5 | 96 tests | P0C1X8 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | AAK1 | abx145892 | AP2 Associated Protein Kinase 1 (AAK1) Antibody | Human | Polyclonal | Rabbit | AP2 Associated Protein Kinase 1 (AAK1) | Unconjugated | ELISA, WB | 337.5 | 100 µg | Q2M2I8 | RUO | |
Abbexa | AAK1 | abx431861 | AP2 Associated Protein Kinase 1 (AAK1) Antibody | Human | Polyclonal | Goat | AP2 Associated Protein Kinase 1 (AAK1) | Unconjugated | P-ELISA, WB | 387.5 | 200 µl | RUO | ||
Abbexa | AAK1 | abx315042 | AP2 Associated Protein Kinase 1 (AAK1) Antibody (Biotin) | Human | Polyclonal | Rabbit | AP2 Associated Protein Kinase 1 (AAK1) | Biotin | ELISA | 162.5 | 20 µg | Q2M2I8 | RUO | |
Abbexa | AAK1 | abx315041 | AP2 Associated Protein Kinase 1 (AAK1) Antibody (FITC) | Human | Polyclonal | Rabbit | AP2 Associated Protein Kinase 1 (AAK1) | FITC | 162.5 | 20 µg | Q2M2I8 | RUO | ||
Abbexa | AAK1 | abx315040 | AP2 Associated Protein Kinase 1 (AAK1) Antibody (HRP) | Human | Polyclonal | Rabbit | AP2 Associated Protein Kinase 1 (AAK1) | HRP | ELISA | 162.5 | 20 µg | Q2M2I8 | RUO | |
Abbexa | AAK1 | abx318210 | AP2 Associated Protein Kinase 1 (AAK1) Antibody | Human | Polyclonal | Rabbit | AP2 Associated Protein Kinase 1 (AAK1) | Unconjugated | ELISA, WB, IHC, IF/ICC | 162.5 | 20 µg | Q2M2I8 | RUO | |
Abbexa | AAK1 | abx013644 | AP2 Associated Protein Kinase 1 (AAK1) Antibody | Human | Polyclonal | Rabbit | AP2 Associated Protein Kinase 1 (AAK1) | Unconjugated | ELISA, WB | 43.75 | 10 µg | Q2M2I8 | RUO | |
Abbexa | AAK1 | abx330065 | AP2 Associated Protein Kinase 1 (AAK1) Antibody | Human | Polyclonal | Rabbit | AP2 Associated Protein Kinase 1 (AAK1) | Unconjugated | ELISA, WB, IHC, IF/ICC | 187.5 | 50 µg | Q2M2I8 | RUO | |
Abbexa | AAK1 | abx028171 | AP2 Associated Protein Kinase 1 (AAK1) Antibody | Mouse | Polyclonal | Rabbit | AP2 Associated Protein Kinase 1 (AAK1) | Unconjugated | ELISA, WB, IHC | 250 | 80 µl | Q3UHJ0 | RUO |
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