AP2 Associated Protein Kinase 1 (AAK1) Antibody

357.5€ (100 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
AP2 Associated Protein Kinase 1 (AAK1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx145892
tested applications
ELISA, WB
Description
AAK1 Antibody is a Rabbit Polyclonal against AAK1.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | AP2 Associated Protein Kinase 1 (AAK1) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Purified by antigen affinity column chromatography. |
Size 1 | 100 µg |
Size 2 | 1 mg |
Form | Lyophilized |
Tested Applications | ELISA, WB |
Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
Availability | Shipped within 7-15 working days. |
Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q2M2I8 |
Alias | AAK1,AP2 associated kinase 1 |
Background | Antibody anti-AAK1 |
Status | RUO |
Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
AAK1, also known as AP2 Associated Protein Kinase 1, is a serine/threonine protein kinase encoded by the AAK1 gene. It is part of the NAK (Numb-Associated Kinase) family of protein kinases and is involved in various cellular processes, including endocytosis, vesicle trafficking, and signaling pathways.AAK1, is involved in endocytosis, vesicle trafficking, and signaling pathways. It regulates clathrin-mediated endocytosis by phosphorylating key components of the endocytic machinery and participates in intracellular vesicle trafficking and signaling cascades. Dysregulation of AAK1 has been implicated in cancer, neurological disorders, and infectious diseases, highlighting its significance as a potential therapeutic target in various pathological conditions. Further research into the molecular mechanisms underlying AAK1 function and its implications for disease may provide insights into novel therapeutic strategies for treating these conditions.
Related Products

Human AAK1 (AP2-associated protein kinase 1) ELISA Kit
Ver Producto
AP2 Associated Protein Kinase 1 (AAK1) Antibody
Rabbit polyclonal antibody against AAK1 protein. Immunogen region is Internal.
Ver Producto
AP2 Associated Protein Kinase 1 (AAK1) Antibody
Aak1 phosphorylates the AP2M1/mu2 subunit of the adaptor protein complex 2 (AP-2). May play a role in regulating aspects of clathrin-mediated endocytosis (By similarity).
Ver Producto