AP2 Associated Protein Kinase 1 (AAK1) Antibody
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935106861
info@markelab.com
Precio
357.5€ (100 µg)
Antibody anti-AAK1
proveedor
Abbexareference
abx145892Tested Applications
ELISA, WBreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
AAK1 Antibody is a Rabbit Polyclonal against AAK1.
Background
AAK1, also known as AP2 Associated Protein Kinase 1, is a serine/threonine protein kinase encoded by the AAK1 gene. It is part of the NAK (Numb-Associated Kinase) family of protein kinases and is involved in various cellular processes, including endocytosis, vesicle trafficking, and signaling pathways.AAK1, is involved in endocytosis, vesicle trafficking, and signaling pathways. It regulates clathrin-mediated endocytosis by phosphorylating key components of the endocytic machinery and participates in intracellular vesicle trafficking and signaling cascades. Dysregulation of AAK1 has been implicated in cancer, neurological disorders, and infectious diseases, highlighting its significance as a potential therapeutic target in various pathological conditions. Further research into the molecular mechanisms underlying AAK1 function and its implications for disease may provide insights into novel therapeutic strategies for treating these conditions.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
AP2 Associated Protein Kinase 1 (AAK1)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Lyophilized
tested applications
ELISA, WB
purification
Purified by antigen affinity column chromatography.
recommended dilution
ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
buffer
Prior to lyophilization: 1% BSA and 0.02% NaN3.
size 1
100 µg
size 2
1 mg
storage
Store at -20 °C. Avoid repeated freeze/thaw cycles.
or code
AAK1
dry ice
No
availability
Shipped within 7-15 working days.
alias
AAK1,AP2 associated kinase 1
uniprot id
note
Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. -
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