AP2 Associated Protein Kinase 1 (AAK1) Antibody
442€ (200 µl)
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935106861
info@markelab.com
name
AP2 Associated Protein Kinase 1 (AAK1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx431861
tested applications
P-ELISA, WB
Description
AAK1 Antibody is a Goat Polyclonal antibody against AAK1.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: AP2 Associated Protein Kinase 1 (AAK1) Immunogen: abx616041 - Internal region: C-GSPRTSQQNVYNPSE |
| Host | Goat |
| Reactivity | Human |
| Assay Type | Concentration: 0.5 mg/ml |
| Recommended Dilution | P-ELISA: 1/16000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Size 1 | 200 µl |
| Form | Liquid |
| Tested Applications | P-ELISA, WB |
| Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 22848, 269774, 500244 |
| NCBI Accession | NP_055726.3 |
| Alias | AAK1,AP2 associated kinase 1 |
| Background | Antibody anti-AAK1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
AAK1, also known as AP2 Associated Protein Kinase 1, is a serine/threonine protein kinase encoded by the AAK1 gene. It is part of the NAK (Numb-Associated Kinase) family of protein kinases and is involved in various cellular processes, including endocytosis, vesicle trafficking, and signaling pathways.AAK1, is involved in endocytosis, vesicle trafficking, and signaling pathways. It regulates clathrin-mediated endocytosis by phosphorylating key components of the endocytic machinery and participates in intracellular vesicle trafficking and signaling cascades. Dysregulation of AAK1 has been implicated in cancer, neurological disorders, and infectious diseases, highlighting its significance as a potential therapeutic target in various pathological conditions. Further research into the molecular mechanisms underlying AAK1 function and its implications for disease may provide insights into novel therapeutic strategies for treating these conditions.
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