AP2 Associated Protein Kinase 1 (AAK1) Antibody

Este producto es parte de AAK1 - AP2 Associated Protein Kinase 1
AP2 Associated Protein Kinase 1 (AAK1) Antibody

Pida mas información

935106861

info@markelab.com

Precio

292.5€ (80 µl)

Antibody anti-AAK1

proveedor

Abbexa

reference

abx028171

Tested Applications

ELISA, WB, IHC

reactivity

Mouse

status

RUO

clonality

Polyclonal

Descripción

Aak1 phosphorylates the AP2M1/mu2 subunit of the adaptor protein complex 2 (AP-2). May play a role in regulating aspects of clathrin-mediated endocytosis (By similarity).


Background

AAK1, also known as AP2 Associated Protein Kinase 1, is a serine/threonine protein kinase encoded by the AAK1 gene. It is part of the NAK (Numb-Associated Kinase) family of protein kinases and is involved in various cellular processes, including endocytosis, vesicle trafficking, and signaling pathways.AAK1, is involved in endocytosis, vesicle trafficking, and signaling pathways. It regulates clathrin-mediated endocytosis by phosphorylating key components of the endocytic machinery and participates in intracellular vesicle trafficking and signaling cascades. Dysregulation of AAK1 has been implicated in cancer, neurological disorders, and infectious diseases, highlighting its significance as a potential therapeutic target in various pathological conditions. Further research into the molecular mechanisms underlying AAK1 function and its implications for disease may provide insights into novel therapeutic strategies for treating these conditions.

Características del producto

category

Primary Antibodies


clonality

Polyclonal


reactivity

Mouse


immunogen target

AP2 Associated Protein Kinase 1 (AAK1)


host

Rabbit


isotype

IgG


conjugation

Unconjugated


form

Liquid


tested applications

ELISA, WB, IHC


purification

Purified through a protein A column, followed by peptide affinity purification.


recommended dilution

WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.


buffer

PBS containing 0.09% sodium azide.


size 1

80 µl


size 2

400 µl


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

AAK1


dry ice

No


availability

Shipped within 5-10 working days.


alias

AAK1,AP2 associated kinase 1


Quizá le pueda interesar

Human AAK1(AP2-associated protein kinase 1) ELISA Kit

Human AAK1(AP2-associated protein kinase 1) ELISA Kit

proveedor

FineTest

reference

EH13909

reactivity

human

status

RUO

Precio a consultar

Ver más

AP2 Associated Protein Kinase 1 (AAK1) Antibody

AP2 Associated Protein Kinase 1 (AAK1) Antibody

proveedor

Abbexa

reference

abx013644

Tested Applications

ELISA, WB

reactivity

Human, Mouse, Rat

status

RUO

clonality

Polyclonal

Rabbit polyclonal antibody against AAK1 protein. Immunogen region is Internal.

52€ (10 µg)

Ver más

AP2 Associated Protein Kinase 1 (AAK1) Antibody

AP2 Associated Protein Kinase 1 (AAK1) Antibody

proveedor

Abbexa

reference

abx028171

Tested Applications

ELISA, WB, IHC

reactivity

Mouse

status

RUO

clonality

Polyclonal

Aak1 phosphorylates the AP2M1/mu2 subunit of the adaptor protein complex 2 (AP-2). May play a role in regulating aspects...

292.5€ (80 µl)

Ver más