WAS Protein Family Member 1 (WASF1) Antibody (Biotin)

Este producto es parte de WASF - WASP family member
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169€ (20 µg)

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935106861
info@markelab.com
name
WAS Protein Family Member 1 (WASF1) Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx317606
tested applications
ELISA

Description

WASF1 Antibody (Biotin) is a Rabbit Polyclonal against WASF1 conjugated to Biotin.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetWAS Protein Family Member 1 (WASF1)
HostRabbit
ReactivityHuman
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationBiotin
IsotypeIgG
Purity> 95%
PurificationPurified by Protein G.
Size 120 µg
Size 250 µg
Size 3100 µg
Size 4200 µg
Size 51 mg
FormLiquid
Tested ApplicationsELISA
Buffer0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
AvailabilityShipped within 5-10 working days.
StorageAliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDQ92558
Gene ID8936
OMIM605035
AliasWAVE,SCAR1,WAVE1,NEDALVS,Actin-binding protein WASF1,Verprolin homology domain-containing protein 1,Wiskott-Aldrich syndrome protein family member 1
BackgroundAntibody anti-WASF1
StatusRUO

Descripción

WASP family member 1 (WASF1) is a member of the WASP family of proteins involved in regulating the actin cytoskeleton in cells WASF1, also known as neural Wiskott–Aldrich syndrome protein, plays a critical role in actin polymerization, which is essential for processes like cell migration, adhesion, and immune response WASF1 activates the Arp2/3 complex, leading to the branching of actin filaments and promoting the formation of cellular protrusions such as lamellipodia and filopodia These structures are vital for cellular movement and tissue development In immune cells, WASF1 is involved in regulating the actin cytoskeleton to enable processes like phagocytosis and the formation of the immune synapse Dysregulation of WASF1 is implicated in various diseases, including immune disorders like Wiskott–Aldrich syndrome and certain cancers, where altered actin dynamics disrupt normal cell function and immune responses

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