WAS Protein Family Member 3 (WASF3) Antibody

Este producto es parte de WASF - WASP family member
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169€ (20 µg)

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935106861
info@markelab.com
name
WAS Protein Family Member 3 (WASF3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx338507
tested applications
ELISA, WB, IHC, IF/ICC

Description

WASF3 Antibody is a Rabbit Polyclonal against WASF3.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetWAS Protein Family Member 3 (WASF3)
HostRabbit
ReactivityHuman
Recommended DilutionWB: 1/500 - 1/5000, IHC: 1/20 - 1/200, IF/ICC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationUnconjugated
IsotypeIgG
Purity> 95%
PurificationPurified by Protein G.
Size 120 µg
Size 250 µg
Size 3100 µg
Size 4200 µg
Size 51 mg
FormLiquid
Tested ApplicationsELISA, WB, IHC, IF/ICC
Buffer0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
AvailabilityShipped within 5-10 working days.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDQ9UPY6
Gene ID10810
AliasSCAR3,WAVE3,Brush-1,Actin-binding protein WASF3,Verprolin homology domain-containing protein 3,Wiskott-Aldrich syndrome protein family member 3
BackgroundAntibody anti-WASF3
StatusRUO

Descripción

WASP family member 3 (WASF3) is a protein that also plays a crucial role in regulating the actin cytoskeleton, influencing processes such as cell migration, cell adhesion, and metastasis WASF3 is distinct in its regulation of actin dynamics compared to WASF1 and WASF2, as it primarily affects the formation of filopodia, which are involved in cell movement and the establishment of cell polarity WASF3 is particularly important in cancer metastasis, where it promotes the migration and invasion of cancer cells through extracellular matrices It is also involved in neurodevelopment and synaptic function, where it helps regulate actin dynamics necessary for neuronal growth and plasticity Dysregulation of WASF3 is implicated in several diseases, including cancer metastasis, where its overexpression leads to increased cell motility and the spread of cancer, as well as neurological disorders related to synaptic dysfunction

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