WAS Protein Family Member 3 (WASF3) Antibody
357.5€ (100 µg)
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name
WAS Protein Family Member 3 (WASF3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx122243
tested applications
ELISA, WB
Description
Rabbit Polyclonal against the WASF3 protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | WAS Protein Family Member 3 (WASF3) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by Protein A/G column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB |
| Buffer | Prior to lyophilization: 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | NP_006637 |
| Alias | SCAR3,WAVE3,Brush-1,Actin-binding protein WASF3,Verprolin homology domain-containing protein 3,Wiskott-Aldrich syndrome protein family member 3 |
| Background | Antibody anti-WASF3 |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
WASP family member 3 (WASF3) is a protein that also plays a crucial role in regulating the actin cytoskeleton, influencing processes such as cell migration, cell adhesion, and metastasis WASF3 is distinct in its regulation of actin dynamics compared to WASF1 and WASF2, as it primarily affects the formation of filopodia, which are involved in cell movement and the establishment of cell polarity WASF3 is particularly important in cancer metastasis, where it promotes the migration and invasion of cancer cells through extracellular matrices It is also involved in neurodevelopment and synaptic function, where it helps regulate actin dynamics necessary for neuronal growth and plasticity Dysregulation of WASF3 is implicated in several diseases, including cancer metastasis, where its overexpression leads to increased cell motility and the spread of cancer, as well as neurological disorders related to synaptic dysfunction
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