WAS Protein Family Member 3 (WASF3) Antibody

Background

WASP family member 3 (WASF3) is a protein that also plays a crucial role in regulating the actin cytoskeleton, influencing processes such as cell migration, cell adhesion, and metastasis WASF3 is distinct in its regulation of actin dynamics compared to WASF1 and WASF2, as it primarily affects the formation of filopodia, which are involved in cell movement and the establishment of cell polarity WASF3 is particularly important in cancer metastasis, where it promotes the migration and invasion of cancer cells through extracellular matrices It is also involved in neurodevelopment and synaptic function, where it helps regulate actin dynamics necessary for neuronal growth and plasticity Dysregulation of WASF3 is implicated in several diseases, including cancer metastasis, where its overexpression leads to increased cell motility and the spread of cancer, as well as neurological disorders related to synaptic dysfunction