WAS Protein Family Member 1 (WASF1) Antibody
273€ (200 µl)
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935106861
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name
WAS Protein Family Member 1 (WASF1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx430468
tested applications
P-ELISA
Description
WASF1 Antibody is a Goat Polyclonal antibody against WASF1.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | WAS Protein Family Member 1 (WASF1) |
| Host | Goat |
| Recommended Dilution | P-ELISA: 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Size 1 | 200 µl |
| Form | Liquid |
| Tested Applications | P-ELISA |
| Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 8936, 83767, 294568 |
| NCBI Accession | NP_003922.1 |
| Alias | WAVE,SCAR1,WAVE1,NEDALVS,Actin-binding protein WASF1,Verprolin homology domain-containing protein 1,Wiskott-Aldrich syndrome protein family member 1 |
| Background | Antibody anti-WASF1 |
| Status | RUO |
| Note | Concentration: 0.5 mg/ml - |
Descripción
WASP family member 1 (WASF1) is a member of the WASP family of proteins involved in regulating the actin cytoskeleton in cells WASF1, also known as neural Wiskott–Aldrich syndrome protein, plays a critical role in actin polymerization, which is essential for processes like cell migration, adhesion, and immune response WASF1 activates the Arp2/3 complex, leading to the branching of actin filaments and promoting the formation of cellular protrusions such as lamellipodia and filopodia These structures are vital for cellular movement and tissue development In immune cells, WASF1 is involved in regulating the actin cytoskeleton to enable processes like phagocytosis and the formation of the immune synapse Dysregulation of WASF1 is implicated in various diseases, including immune disorders like Wiskott–Aldrich syndrome and certain cancers, where altered actin dynamics disrupt normal cell function and immune responses
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