WAS Protein Family Member 1 (WASF1) Antibody

Este producto es parte de WASF - WASP family member
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273€ (200 µl)

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935106861
info@markelab.com
name
WAS Protein Family Member 1 (WASF1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx430468
tested applications
P-ELISA

Description

WASF1 Antibody is a Goat Polyclonal antibody against WASF1.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
WAS Protein Family Member 1 (WASF1)
Host
Goat
Recommended Dilution
P-ELISA: 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Size 1
200 µl
Form
Liquid
Tested Applications
P-ELISA
Buffer
Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Gene ID
8936, 83767, 294568
NCBI Accession
NP_003922.1
Alias
WAVE,SCAR1,WAVE1,NEDALVS,Actin-binding protein WASF1,Verprolin homology domain-containing protein 1,Wiskott-Aldrich syndrome protein family member 1
Background
Antibody anti-WASF1
Status
RUO
Note
Concentration: 0.5 mg/ml - 

Descripción

WASP family member 1 (WASF1) is a member of the WASP family of proteins involved in regulating the actin cytoskeleton in cells WASF1, also known as neural Wiskott–Aldrich syndrome protein, plays a critical role in actin polymerization, which is essential for processes like cell migration, adhesion, and immune response WASF1 activates the Arp2/3 complex, leading to the branching of actin filaments and promoting the formation of cellular protrusions such as lamellipodia and filopodia These structures are vital for cellular movement and tissue development In immune cells, WASF1 is involved in regulating the actin cytoskeleton to enable processes like phagocytosis and the formation of the immune synapse Dysregulation of WASF1 is implicated in various diseases, including immune disorders like Wiskott–Aldrich syndrome and certain cancers, where altered actin dynamics disrupt normal cell function and immune responses

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