WAS Protein Family Member 1 Phospho-Tyr125 (WASF1 pY125) Antibody
429€ (100 µl)
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935106861
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name
WAS Protein Family Member 1 Phospho-Tyr125 (WASF1 pY125) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx333069
tested applications
ELISA, WB, IHC
Description
WASF1 (pY125) Antibody is a Rabbit Polyclonal against WASF1 (pY125).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | WAS Protein Family Member 1 Phospho-Tyr125 (WASF1 pY125) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Assay Data | Modification: Phosphorylation // Target Modification: Tyr125 |
| Recommended Dilution | WB: 1/500 - 1/3000, IHC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS (without Mg2+ and Ca2+), pH 7.4, containing 150mM NaCl, 0.02% sodium azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q92558 |
| Gene ID | 8936 |
| Alias | WAVE,SCAR1,WAVE1,NEDALVS,Actin-binding protein WASF1,Verprolin homology domain-containing protein 1,Wiskott-Aldrich syndrome protein family member 1 |
| Background | Antibody anti-WASF1 |
| Status | RUO |
Descripción
WASP family member 1 (WASF1) is a member of the WASP family of proteins involved in regulating the actin cytoskeleton in cells WASF1, also known as neural Wiskott–Aldrich syndrome protein, plays a critical role in actin polymerization, which is essential for processes like cell migration, adhesion, and immune response WASF1 activates the Arp2/3 complex, leading to the branching of actin filaments and promoting the formation of cellular protrusions such as lamellipodia and filopodia These structures are vital for cellular movement and tissue development In immune cells, WASF1 is involved in regulating the actin cytoskeleton to enable processes like phagocytosis and the formation of the immune synapse Dysregulation of WASF1 is implicated in various diseases, including immune disorders like Wiskott–Aldrich syndrome and certain cancers, where altered actin dynamics disrupt normal cell function and immune responses
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