Vasoactive Intestinal Peptide Receptor (VIPR1) Antibody
292.5€ (80 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Vasoactive Intestinal Peptide Receptor (VIPR1) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx031167
Tested Applications
ELISA, WB
Description
This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate cyclase.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Vasoactive Intestinal Peptide Receptor (VIPR1) Immunogen: KLH-conjugated synthetic peptide between 305-334 amino acids from the C-terminal region of human VIPR1. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 51.5 kDa |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P32241 |
| Alias | VIPR1,Pituitary adenylate cyclase-activating polypeptide type II receptor,PACAP type II receptor,PACAP-R-2,PACAP-R2,VPAC1 |
| Background | Antibody anti-VIPR1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
VIPR1 is a G protein-coupled receptor activated by vasoactive intestinal peptide (VIP), a neuropeptide involved in regulating smooth muscle relaxation, vasodilation, and neurotransmission. VIPR1 couples to Gs proteins, stimulating adenylate cyclase and increasing cAMP levels, leading to relaxation of smooth muscle cells, dilation of blood vessels, and modulation of gastrointestinal motility. VIPR1 is primarily expressed in the smooth muscle of the gastrointestinal tract, blood vessels, and the central nervous system, where it plays a role in regulating vascular tone, intestinal motility, and neurotransmitter release. VIP has a significant role in regulating inflammation and immune responses, and VIPR1 signaling is involved in modulating immune cell functions. Dysregulation of VIPR1 signaling has been implicated in inflammatory diseases, gastrointestinal disorders, and cardiovascular diseases. Agonists targeting VIPR1 are being investigated for their potential to treat diseases involving smooth muscle contraction and inflammation, such as asthma, irritable bowel syndrome (IBS), and hypertension.
Productos relacionados
Vasoactive Intestinal Peptide Receptor (VIPR1) Antibody
This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is i…
Ver producto
Vasoactive Intestinal Peptide Receptor 1 (VIPR1) Antibody
Vasoactive Intestinal Peptide Receptor 1 Antibody is a Rabbit Polyclonal against Vasoactive Intestinal Peptide Receptor …
Ver producto
Human Vasoactive Intestinal Peptide Receptor 1 (VIPR1) ELISA Kit
Human Vasoactive Intestinal Peptide Receptor 1 (VIPR1) ELISA Kit is an ELISA Kit for the in vitro quantitative measureme…
Ver producto