Vasoactive Intestinal Peptide Receptor 1 (VIPR1) Antibody
260€ (50 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Vasoactive Intestinal Peptide Receptor 1 (VIPR1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx213688
tested applications
ELISA, IHC
Description
VIPR1 Antibody is a Rabbit Polyclonal against VIPR1.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Vasoactive Intestinal Peptide Receptor 1 (VIPR1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1/1000 - 1/2000, IHC: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P32241 |
| Gene ID | 7433 |
| Alias | VIPR1,Pituitary adenylate cyclase-activating polypeptide type II receptor,PACAP type II receptor,PACAP-R-2,PACAP-R2,VPAC1 |
| Background | Antibody anti-VIPR1 |
| Status | RUO |
Descripción
VIPR1 is a G protein-coupled receptor activated by vasoactive intestinal peptide (VIP), a neuropeptide involved in regulating smooth muscle relaxation, vasodilation, and neurotransmission. VIPR1 couples to Gs proteins, stimulating adenylate cyclase and increasing cAMP levels, leading to relaxation of smooth muscle cells, dilation of blood vessels, and modulation of gastrointestinal motility. VIPR1 is primarily expressed in the smooth muscle of the gastrointestinal tract, blood vessels, and the central nervous system, where it plays a role in regulating vascular tone, intestinal motility, and neurotransmitter release. VIP has a significant role in regulating inflammation and immune responses, and VIPR1 signaling is involved in modulating immune cell functions. Dysregulation of VIPR1 signaling has been implicated in inflammatory diseases, gastrointestinal disorders, and cardiovascular diseases. Agonists targeting VIPR1 are being investigated for their potential to treat diseases involving smooth muscle contraction and inflammation, such as asthma, irritable bowel syndrome (IBS), and hypertension.
Related Products
Human VIPR1(Vasoactive intestinal polypeptide receptor 1) ELISA Kit
Ver Producto
anti- VIPR1 antibody
This is a receptor for VIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The affinity is VIP = PACAP-27 > PACAP-38.
Ver Producto
Vasoactive Intestinal Peptide Receptor (VIPR1) Antibody
This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate cyclase.
Ver Producto