V-Set And Immunoglobulin Domain Containing Protein 2 (VSIG2) Antibody
357.5€ (100 µg)
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Name
V-Set And Immunoglobulin Domain Containing Protein 2 (VSIG2) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx037978
Tested Applications
ELISA, WB, IHC
Description
Rabbit Polyclonal against the VSIG2 protein.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: V-Set And Immunoglobulin Domain Containing Protein 2 (VSIG2) Immunogen: Recombinant fragment corresponding to 48-242 AA of human VSIG2. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/1000 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 30 kDa, 34 kDa |
| Purification | Purified by Protein A/G column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | CTH,CTXL,Cortical thymocyte-like protein,CT-like protein |
| Background | Antibody anti-VSIG2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
V-set and immunoglobulin domain containing 2 (VSIG2) is a member of the immunoglobulin superfamily and is primarily expressed in epithelial cells across various tissues, particularly in the gastrointestinal and urogenital tracts. This protein is involved in cell adhesion and potentially plays roles in epithelial cell organization and barrier formation. It has been suggested to function as a mediator of intercellular communication and contribute to tissue integrity by maintaining cell polarity and suppressing excessive cell migration. VSIG2 is also of interest in cancer research due to its altered expression in various malignancies, such as colorectal and gastric cancers, where it is hypothesized to influence tumor progression and metastasis. Furthermore, VSIG2 may have immunomodulatory roles, interacting with immune cells to regulate inflammatory responses and maintaining epithelial-immune system homeostasis. Current studies explore its potential as a biomarker for cancer prognosis and a target for therapeutic interventions aimed at modulating tumor-immune interactions. The exact mechanisms of VSIG2 signaling remain an area of active investigation, particularly in its roles in epithelial tissue maintenance and cancer biology.
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