Uroplakin-3b (UPK3B) Antibody

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Description
UPK3B Antibody is a Rabbit Polyclonal against UPK3B.
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Product specifications
Category | Primary Antibodies |
Immunogen Target | Uroplakin-3b (UPK3B) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | ELISA: 1/500 - 1/10000, WB: 1/1000 - 1/4000, IHC: 1/5 - 1/20. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Antigen Affinity Chromatography. |
Size 1 | 50 µl |
Size 2 | 100 µl |
Form | Liquid |
Tested Applications | ELISA, WB, IHC |
Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q9BT76 |
Gene ID | 105375355 |
Background | Antibody anti-UPK3B |
Status | RUO |
Descripción
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UPK3B antibody
Component of the asymmetric unit membrane(AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence(By similarity).
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Uroplakin-3b (UPK3B) Antibody
UPK3B is a minor component of the apical plaques of mammalian urothelium that binds and dimerizes with uroplakin-1b (UPK1B; MIM 602380), one of the major conserved urothelium membrane proteins. The other major conserved integral membrane proteins of urothelial plaques are UPK1A (MIM 611557), UPK2 (MIM 611558), and UPK3A (MIM 611559) (Deng et al., 2002 [PubMed 12446744]).[supplied by OMIM].
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