UPK3B antibody
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Description
Component of the asymmetric unit membrane(AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence(By similarity).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | uroplakin 3B (UPK3B) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | IHC: 1:20-1:200; IP: 1:200-1:1000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 34 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9BT76 |
| Gene ID | 80761 |
| Alias | Uroplakin-3b (UP3b),Uroplakin IIIb (UPIIIb),p35,UPK3B |
| Background | Antibody anti-UPK3B |
| Status | RUO |
| Note | Mol. Weight 34 kDa |
Descripción
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UPK3B antibody
Component of the asymmetric unit membrane(AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence(By similarity).
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Uroplakin-3b (UPK3B) Antibody
UPK3B is a minor component of the apical plaques of mammalian urothelium that binds and dimerizes with uroplakin-1b (UPK1B; MIM 602380), one of the major conserved urothelium membrane proteins. The other major conserved integral membrane proteins of urothelial plaques are UPK1A (MIM 611557), UPK2 (MIM 611558), and UPK3A (MIM 611559) (Deng et al., 2002 [PubMed 12446744]).[supplied by OMIM].
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