Ubiquitin Carboxyl Terminal Hydrolase L4 (UCHL4) Antibody
299€ (100 µl)
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935106861
info@markelab.com
name
Ubiquitin Carboxyl Terminal Hydrolase L4 (UCHL4) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx129331
tested applications
WB, IHC, IF/ICC
Description
Ubiquitin Carboxyl Terminal Hydrolase L4 Antibody is a Rabbit Polyclonal against Ubiquitin Carboxyl Terminal Hydrolase L4.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Ubiquitin Carboxyl Terminal Hydrolase L4 (UCHL4) |
| Host | Rabbit |
| Reactivity | Mouse |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | Ubiquitin thioesterase L4 |
| Background | Antibody anti-UCHL4 |
| Status | RUO |
Descripción
Ubiquitin C-Terminal Hydrolase L4 (UCHL4) is a member of the deubiquitinating enzyme family, which plays a critical role in the ubiquitin-proteasome system by removing ubiquitin moieties from ubiquitinated proteins. This process regulates protein degradation, turnover, and signaling pathways. UCHL4 is specifically involved in maintaining cellular ubiquitin homeostasis, thus influencing various cellular processes, including cell cycle progression, DNA repair, and stress responses. Dysregulation of UCHL4 activity has been implicated in pathological conditions such as cancer, where it may affect the stability of key oncogenes or tumor suppressors. Additionally, UCHL4 might have a role in neurodegenerative diseases through its function in protein quality control and aggregation prevention. Understanding its precise biological mechanisms is essential for exploring its potential as a therapeutic target in diseases associated with ubiquitin pathway dysregulation.
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