Ubiquitin-40S Ribosomal Protein S27a (RPS27A) Antibody
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Description
Ubiquitin-40S Ribosomal Protein S27a (RPS27A) Antibody is a Rabbit Polyclonal antibody against Ubiquitin-40S Ribosomal Protein S27a (RPS27A). Ubiquitin, a highly conserved protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome, is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin fused to an unrelated proteinThis gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein S27a at the C terminusWhen expressed in yeast, the protein is post-translationally processed, geneRating free ubiquitin monomer and ribosomal protein S27aRibosomal protein S27a is a component of the 40S subunit of the ribosome and belongs to the S27AE family of ribosomal proteinsIt contains C4-type zinc finger domains and is located in the cytoplasmPseudogenes derived from this gene are present in the genomeAs with ribosomal protein S27a, ribosomal protein L40 is also synthesized as a fusion protein with ubiquitin; similarly, ribosomal protein S30 is synthesized as a fusion protein with the ubiquitin-like protein fubiMultiple alternatively spliced transcript variants that encode the same proteins have been identified.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Ubiquitin-40S Ribosomal Protein S27a (RPS27A) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P62979 |
| Gene ID | 6233 |
| Background | Antibody anti-RPS27A |
| Status | RUO |
Descripción
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RPS27A antibody
RPS27A, also named as UBA80 and UBCEP1, can be cleaved into two chains Ubiquitin and 40S ribosomal protein S27a. Ubiquitin is a highly conserved 76-amino acid protein that plays a key role in protein degradation. Ubiquitin is synthesized as precursor proteins that consist either of polyubiquitin chains that are cleaved into moieties of the UBB or UBC types, or single ubiquitin moieties fused 5-prime to unrelated carboxyl extension proteins (UBA type) such as UBA52 and UBA80 (RPS27A) [PMID:10772958]
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Ubiquitin-40S Ribosomal Protein S27a (RPS27A) Antibody
Ubiquitin-40S Ribosomal Protein S27a (RPS27A) Antibody is a Rabbit Polyclonal antibody against Ubiquitin-40S Ribosomal Protein S27a (RPS27A). Ubiquitin, a highly conserved protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome, is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein S27a at the C terminus. When expressed in yeast, the protein is post-translationally processed, generating free ubiquitin monomer and ribosomal protein S27a. Ribosomal protein S27a is a component of the 40S subunit of the ribosome and belongs to the S27AE family of ribosomal proteins. It contains C4-type zinc finger domains and is located in the cytoplasm. Pseudogenes derived from this gene are present in the genome. As with ribosomal protein S27a, ribosomal protein L40 is also synthesized as a fusion protein with ubiquitin; similarly, ribosomal protein S30 is synthesized as a fusion protein with the ubiquitin-like protein fubi. Multiple alternatively spliced transcript variants that encode the same proteins have been identified.[provided by RefSeq, Sep 2008].
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Ubiquitin-40S Ribosomal Protein S27a (RPS27A) Antibody
Ubiquitin-40S Ribosomal Protein S27a (RPS27A) Antibody is a Rabbit Polyclonal antibody against Ubiquitin-40S Ribosomal Protein S27a (RPS27A). Ubiquitin, a highly conserved protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome, is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin fused to an unrelated proteinThis gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein S27a at the C terminusWhen expressed in yeast, the protein is post-translationally processed, geneRating free ubiquitin monomer and ribosomal protein S27aRibosomal protein S27a is a component of the 40S subunit of the ribosome and belongs to the S27AE family of ribosomal proteinsIt contains C4-type zinc finger domains and is located in the cytoplasmPseudogenes derived from this gene are present in the genomeAs with ribosomal protein S27a, ribosomal protein L40 is also synthesized as a fusion protein with ubiquitin; similarly, ribosomal protein S30 is synthesized as a fusion protein with the ubiquitin-like protein fubiMultiple alternatively spliced transcript variants that encode the same proteins have been identified.
Ver Producto