Tyrosine-Protein Kinase Receptor TYRO3 (TYRO3) Antibody

Este producto es parte de TYRO3 protein tyrosine kinase
Tyrosine-Protein Kinase Receptor TYRO3 (TYRO3) Antibody

Pida mas información

935106861

info@markelab.com

Precio

362.5€ (100 µl)

Antibody anti-TYRO3

proveedor

Abbexa

reference

abx012308

Tested Applications

ELISA, IF/ICC

reactivity

Human

status

RUO

clonality

Monoclonal

Descripción

Tyro3 (also known as Sky and Rse), with 890-amino acid protein (about 98kDa), belongs to the Axl/Tyro3 family of receptor tyrosine kinases, which also includes Axl and Mer.Gas6 (growth arrest-specific gene-6) is a ligand for all members of the Axl family and they play essential roles in spermatogenesis, immunoregulation, and phagocytosis.Tyro3 was expressed at high levels during postnatal development and in the adult in the cortex.Tyro3 and Gas6 have neurotrophic roles in the nervous system.In addition, the signalling interactions of Axl and Tyro3 may play roles in tumourigenesis, inflammation as well as other cell proliferative diseases.


Background

TYRO3, a member of the TAM receptor tyrosine kinase family, plays a critical role in various cellular processes, including cell survival, proliferation, and immune regulation. The TAM family consists of three receptors: TYRO3, AXL, and MERTK, all of which are characterized by their involvement in modulating immune responses and maintaining tissue homeostasis. TYRO3 is encoded by the TYRO3 gene located on chromosome 15q15 in humans and is widely expressed in tissues such as the brain, reproductive organs, and the immune system. Understanding the structural and functional properties of TYRO3 is crucial for elucidating its roles in health and disease.

Características del producto

category

Primary Antibodies


clonality

Monoclonal


reactivity

Human


immunogen target

Tyrosine-Protein Kinase Receptor TYRO3 (TYRO3)


host

Mouse


conjugation

Unconjugated


form

Liquid


tested applications

ELISA, IF/ICC


purification

Unpurified ascites.


buffer

Ascitic fluid containing 0.03% sodium azide.


size 1

100 µl


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

TYRO3


dry ice

No


availability

Shipped within 5-10 working days.


alias

BYK,Dtk,RSE,Rek,Sky,Tif,Etk-2


note

This product is for research use only.


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reactivity

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status

RUO

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proveedor

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reference

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Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Monoclonal

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