Tyrosine-Protein Kinase Mer (MERTK) Antibody
52€ (10 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Tyrosine-Protein Kinase Mer (MERTK) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx015165
tested applications
ELISA, WB
Description
Rabbit polyclonal antibody against MERTK protein. Immunogen region is N-terminal.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Tyrosine-Protein Kinase Mer (MERTK) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/500 - 1/3000, ELISA: 1/5000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q12866 |
| Gene ID | 10461 |
| NCBI Accession | NP_006334.2 |
| OMIM | 604705 |
| Alias | MER,RP38,c-Eyk,c-mer,Tyro12,Receptor tyrosine kinase MerTK,Proto-oncogene c-Mer |
| Background | Antibody anti-MERTK |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
MERTK (MER Proto-Oncogene, Tyrosine Kinase) is a member of the TAM (TYRO3, AXL, and MERTK) receptor tyrosine kinase family, which plays a crucial role in the regulation of immune response, cell survival, migration, and phagocytosis. This gene was identified due to its homology with the avian oncogene v-Mer and is involved in the clearance of apoptotic cells and immune tolerance. The MERTK protein is primarily expressed in macrophages, dendritic cells, and retinal pigment epithelial cells. Dysregulation of MERTK has been implicated in various diseases, including cancer, autoimmune disorders, and retinal degenerative diseases.
Related Products
Human Mer/MERTK(Tyrosine-protein kinase Mer) ELISA Kit
Ver Producto
Tyrosine-Protein Kinase Mer (MERTK) Antibody
MERTK Antibody is a Rabbit Polyclonal antibody against MERTK.
Ver Producto
Tyrosine-Protein Kinase Mer (MERTK) Antibody
Rabbit polyclonal antibody against MERTK protein. Immunogen region is N-terminal.
Ver Producto