Tyrosine-Protein Kinase Mer (MERTK) Antibody
312€ (60 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Tyrosine-Protein Kinase Mer (MERTK) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx004167
Tested Applications
IF/ICC
Description
MERTK Antibody is a Rabbit Polyclonal antibody against MERTK.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Tyrosine-Protein Kinase Mer (MERTK) Immunogen: Recombinant fusion protein corresponding to human MERTK |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | IF/ICC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q12866 |
| Gene ID | 10461 |
| NCBI Accession | NP_006334.2 |
| OMIM | 604705 |
| Alias | MER,RP38,c-Eyk,c-mer,Tyro12,Receptor tyrosine kinase MerTK,Proto-oncogene c-Mer |
| Background | Antibody anti-MERTK |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
MERTK (MER Proto-Oncogene, Tyrosine Kinase) is a member of the TAM (TYRO3, AXL, and MERTK) receptor tyrosine kinase family, which plays a crucial role in the regulation of immune response, cell survival, migration, and phagocytosis. This gene was identified due to its homology with the avian oncogene v-Mer and is involved in the clearance of apoptotic cells and immune tolerance. The MERTK protein is primarily expressed in macrophages, dendritic cells, and retinal pigment epithelial cells. Dysregulation of MERTK has been implicated in various diseases, including cancer, autoimmune disorders, and retinal degenerative diseases.
Productos relacionados
Tyrosine-Protein Kinase Mer (MERTK) Antibody
MERTK Antibody is a Rabbit Polyclonal antibody against MERTK.…
Ver producto
Tyrosine-Protein Kinase Mer (MERTK) Antibody
Rabbit polyclonal antibody against MERTK protein. Immunogen region is N-terminal.…
Ver producto
Tyrosine-Protein Kinase Mer (MERTK) Antibody
MER (c-mer proto-oncogene tyrosine kinase) is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transme…
Ver producto