Tyrosine Kinase 2 (Tyk2) Antibody
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Description
Tyrosine Kinase 2 Antibody is a Rabbit Polyclonal against Tyrosine Kinase 2.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Tyrosine Kinase 2 (TYK2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1-5 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P29597 |
| Gene ID | 7297 |
| OMIM | 176941 |
| Background | Antibody anti-Tyk2 |
| Status | RUO |
Descripción
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Tyrosine Kinase 2 (Tyk2) Antibody
TYK2 (tyrosine kinase 2),with 1187-amino acid protein (about 131kDa), belongs to the family of non-receptor janus tyrosine kinases, which also includes Jak1, Jak2, and Jak3. Kinases of the Jak family regulate a spectrum of cellular functions downstream of activated cytokine receptors in the lympho-hematopoietic system. TYK2 is activated by a variety of cytokines: IFN alpha, IFN beta, IL-6, IL-10, IL-12, and IL-13 and promotes IFN gamma production by Th1-type CD4 cells. TYK2 can be viewed as a dual-function Jak, mediating both pro-inflammatory and anti-inflammatory cytokine responses. TYK2 is also an important regulator of lymphoid tumor surveillance.
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Tyrosine Kinase 2 (Tyk2) Antibody
Tyrosine Kinase 2 Antibody is a Rabbit Polyclonal against Tyrosine Kinase 2.
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