TYRO Protein Tyrosine Kinase Binding Protein (TYROBP) Antibody
292.5€ (80 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
TYRO Protein Tyrosine Kinase Binding Protein (TYROBP) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx034547
Tested Applications
ELISA, WB, IHC, FCM
Description
TYROBP encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: TYRO Protein Tyrosine Kinase Binding Protein (TYROBP) Immunogen: KLH-conjugated synthetic peptide between 85-113 amino acids from the C-terminal region of human TYROBP. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 12.2 kDa |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, FCM |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O43914 |
| Background | Antibody anti-TYROBP |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Productos relacionados
TYRO Protein Tyrosine Kinase Binding Protein (TYROBP) Antibody
TYROBP Antibody is a Rabbit Polyclonal antibody against TYROBP. This gene encodes a transmembrane signaling polypeptide …
Ver producto TYRO Protein Tyrosine Kinase Binding Protein (TYROBP) Antibody
TYROBP encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (I…
Ver producto
Human TYRO Protein Tyrosine Kinase Binding Protein (TYROBP) ELISA Kit
Human TYRO Protein Tyrosine Kinase Binding Protein (TYROBP) ELISA Kit is an ELISA Kit for the in vitro quantitative meas…
Ver producto