TYROBP Antibody is a Rabbit Polyclonal antibody against TYROBP. This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene.
Primary Antibodies
Polyclonal
Mouse, Rat
TYRO Protein Tyrosine Kinase Binding Protein (TYROBP)
Rabbit
Unconjugated
Liquid
ELISA
Purified by affinity chromatography.
PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
20 µl
50 µl
100 µl
200 µl
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
TYROBP
No
Shipped within 5-10 working days.
NP_003323.1
This product is for research use only.
Precio a consultar
Ver másTYROBP Antibody is a Rabbit Polyclonal antibody against TYROBP. This gene encodes a transmembrane signaling polypeptide ...
175€ (20 µl)
Ver másTYROBP encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (I...
281.25€ (80 µl)
Ver más