Tumor Necrosis Factor Receptor Superfamily Member 13B / CD267 (TNFRSF13B) Antibody
357.5€ (100 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Tumor Necrosis Factor Receptor Superfamily Member 13B / CD267 (TNFRSF13B) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx038233
Tested Applications
ELISA, WB, IHC
Description
Rabbit Polyclonal against the TNFRSF13B protein.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Tumor Necrosis Factor Receptor Superfamily Member 13B / CD267 (TNFRSF13B) Immunogen: A peptide corresponding to N-terminal region of human TNFRSF13B protein. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 32 kDa |
| Purification | Purified by Protein A/G column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | NM_012452 |
| Alias | Tumor necrosis factor receptor superfamily member 13B,CVID,RYZN,TACI,CD267,CVID2,IGAD2,TNFRSF14B,Transmembrane activator and CAML interactor |
| Background | Antibody anti-TNFRSF13B |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
TNFRSF13B, also known as TACI (Transmembrane Activator and CAML Interactor), is a critical receptor in the immune system, specifically involved in B cell biology. TNFRSF13B belongs to the tumor necrosis factor receptor superfamily (TNFRSF) and plays an essential role in immune regulation by binding ligands such as APRIL (a proliferation-inducing ligand) and BAFF (B-cell activating factor). These interactions are vital for B cell survival, proliferation, and differentiation, particularly in the context of generating long-lasting immune responses and maintaining immune homeostasis. Mutations in TNFRSF13B have been linked to various immunodeficiency disorders, such as Common Variable Immunodeficiency (CVID) and IgA deficiency. These conditions are associated with impaired antibody production, resulting in increased susceptibility to infections and autoimmune complications. Due to its importance in regulating immune responses, TNFRSF13B is studied intensively as a therapeutic target for both immunodeficiency disorders and autoimmune diseases where B cell activity is dysregulated.
Productos relacionados
Tumor Necrosis Factor Receptor Superfamily Member 13B / CD267 (TNFRSF13B) Antibody
TNFRSF13B Antibody is a Rabbit Polyclonal Antibody against TNFRSF13B.…
Ver producto Tumor Necrosis Factor Receptor Superfamily Member 13B / CD267 (TNFRSF13B) Antibody
Rabbit Polyclonal against the TNFRSF13B protein.…
Ver producto Tumor Necrosis Factor Receptor Superfamily Member 13B / CD267 (TNFRSF13B) Antibody
Tumor Necrosis Factor Receptor Superfamily, Member 13B Antibody is a Rabbit Polyclonal antibody against Tumor Necrosis F…
Ver producto