Tumor Necrosis Factor Ligand Superfamily Member 4 (TNFSF4) Antibody

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Description
Tumor Necrosis Factor Ligand Superfamily Member 4 (TNFSF4) Antibody is a Human Monoclonal antibody for the detection of Tumor Necrosis Factor Ligand Superfamily Member 4 (TNFSF4) in Human samples.
Documents del producto
Product specifications
| Category | Primary Antibodies  | 
| Immunogen Target | Tumor Necrosis Factor Ligand Superfamily Member 4 (TNFSF4)  | 
| Host | Human  | 
| Reactivity | Human  | 
| Clonality | Monoclonal  | 
| Conjugation | Unconjugated  | 
| Isotype | IgG4 Kappa  | 
| Clone ID | N283  | 
| Purity | > 95%  | 
| Purification | Purified by Protein A/G affinity chromatography.  | 
| Size 1 | 50 µg  | 
| Size 2 | 100 µg  | 
| Form | Liquid  | 
| Tested Applications | FCM  | 
| Buffer | 0.01 M PBS, pH 7.4.  | 
| Availability | Shipped within 5-12 working days.  | 
| Storage | Store at 4 °C if the entire vial will be used within 1 week. Aliquot and store at -20 °C or -80 °C for long-term storage. Avoid repeated freeze-thaw cycles.  | 
| Dry Ice | No  | 
| UniProt ID | P23510  | 
| Gene ID | 7292  | 
| NCBI Accession | NP_001284491.1  | 
| Alias | Tumor necrosis factor ligand superfamily member 4,GP34,CD252,OX4OL,TXGP1,CD134L,OX-40L,TNLG2B,OX40 ligand,OX40L,TAX transcriptionally-activated glycoprotein 1  | 
| Background | Antibody anti-TNFSF4  | 
| Status | RUO  | 
| Note | Concentration: 1 mg/ml -  | 
Descripción
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The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF4/OX4. It is found to be involved in T cell antigen-presenting cell (APC) interactions. In surface Ig and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells.
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