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Human Tumor Necrosis Factor Ligand Superfamily Member 4 / OX40L (TNFSF4) ELISA Kit
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935106861
info@markelab.com
Precio
618.75€ (96 tests)
Elisa Kits TNFSF4
proveedor
Abbexareference
abx153328Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Tumor Necrosis Factor Ligand Superfamily Member 4 / OX40L (TNFSF4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Tumor Necrosis Factor Ligand Superfamily Member 4 / OX40L (TNFSF4) concentrations in serum, plasma, tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4)No significant cross-reactivity or interference between Tumor Necrosis Factor Ligand Superfamily, Member 4 (TNFSF4) and analogues was observed.
Background
TNFSF4, also known as OX40 ligand (OX40L) or CD252, is a member of the tumor necrosis factor (TNF) superfamily. It plays a crucial role in the immune system by interacting with the OX40 receptor (CD134), primarily expressed on activated T cells. This interaction contributes to T-cell activation, proliferation, and survival, and it is particularly important for the adaptive immune response. OX40L is predominantly expressed on activated antigen-presenting cells, such as dendritic cells, B cells, and macrophages, and its role in enhancing T-cell function is integral to immune response against infections, cancer, and during inflammatory processes. OX40L has gained significant attention for its role in immune checkpoint pathways, which are mechanisms that regulate immune response strength and duration. Because of its function in enhancing T-cell activity, it has been studied as a target for immunotherapies in cancer, autoimmune disorders, and infectious diseases. Additionally, dysregulation of the TNFSF4 gene, which encodes OX40L, has been implicated in several inflammatory and autoimmune diseases, including systemic lupus erythematosus (SLE) and rheumatoid arthritis.
Características del producto
category
ELISA Kits
immunogen target
Tumor Necrosis Factor Ligand Superfamily Member 4 / OX40L (TNFSF4)
reactivity
Human
test range
15.6 pg/ml - 1000 pg/ml
sensitivity
< 6.3 pg/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Serum,Plasma,Tissue homogenates,Other biological fluids
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
Tumor necrosis factor ligand superfamily member 4,GP34,CD252,OX4OL,TXGP1,CD134L,OX-40L,TNLG2B,OX40 ligand,OX40L,TAX transcriptionally-activated glycoprotein 1
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
TNFSF4
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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