Tumor Necrosis Factor Ligand Superfamily Member 14 / LIGHT (TNFSF14) Antibody (APC)

Este producto es parte de TNFSF14 - TNF superfamily member 14
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689€ (100 tests)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Tumor Necrosis Factor Ligand Superfamily Member 14 / LIGHT (TNFSF14) Antibody (APC)
category
Primary Antibodies
provider
Abbexa
reference
abx270629
tested applications
FCM

Description

Tumor Necrosis Factor Ligand Superfamily, Member 14 (TNFSF14) Antibody (APC) is a Rabbit Polyclonal Antibody conjugated to APC against Tumor Necrosis Factor Ligand Superfamily, Member 14 (TNFSF14) for use in flow cytometry.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Tumor Necrosis Factor Ligand Superfamily Member 14 / LIGHT (TNFSF14)
Host
Rabbit
Reactivity
Human
Recommended Dilution
FCM: 1-5 µl/106 cells. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
APC
Isotype
IgG
Purification
Purified by antigen-specific affinity chromatography.
Size 1
100 tests
Size 2
200 tests
Size 3
500 tests
Form
Liquid
Tested Applications
FCM
Buffer
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
Availability
Please enquire.
Storage
Aliquot and store at 2°C to 8°C upon receipt. Avoid exposure to light.
Dry Ice
No
Alias
Tumor necrosis factor ligand superfamily member 14,LTg,CD258,HVEML,LIGHT,Herpes virus entry mediator ligand,Herpesvirus entry mediator ligand
Background
Antibody anti-TNFSF14
Status
RUO

Descripción

TNFSF14, also known as LIGHT (Lymphotoxin-like, exhibits inducible expression, competes with herpes simplex virus glycoprotein D for HVEM, a receptor expressed by T lymphocytes), is a member of the tumor necrosis factor (TNF) superfamily. This ligand is pivotal in immune response modulation and is highly expressed by activated T cells, NK (natural killer) cells, and certain myeloid cells. LIGHT interacts with several receptors, including HVEM (Herpes Virus Entry Mediator), LTβR (Lymphotoxin beta receptor), and DcR3 (Decoy receptor 3), each playing a distinct role in immune signaling pathways. LIGHT’s functions are diverse and are integral to immune cell proliferation, differentiation, survival, and inflammation, with its dysregulation linked to several immune and inflammatory diseases, as well as certain cancers.

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